| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PlcN | cls | HMPREF0758_1988 | HMPREF0758_3528 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.913 |
| PlcN | pgpA | HMPREF0758_1988 | HMPREF0758_0223 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 0.900 |
| PlcN | pgpB-2 | HMPREF0758_1988 | HMPREF0758_3565 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Phosphatidylglycerophosphatase B; COG: COG0671; Pfam: PF01569; InterPro: IPR000326. | 0.901 |
| PlcN | psd | HMPREF0758_1988 | HMPREF0758_0875 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.900 |
| PlcN | yfhB | HMPREF0758_1988 | HMPREF0758_2466 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | HAD hydrolase, family IF; COG: COG0560; InterPro: IPR006435. | 0.900 |
| cls | PlcN | HMPREF0758_3528 | HMPREF0758_1988 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | 0.913 |
| cls | pgpA | HMPREF0758_3528 | HMPREF0758_0223 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 0.917 |
| cls | pgpB-2 | HMPREF0758_3528 | HMPREF0758_3565 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Phosphatidylglycerophosphatase B; COG: COG0671; Pfam: PF01569; InterPro: IPR000326. | 0.910 |
| cls | pgsA | HMPREF0758_3528 | HMPREF0758_4263 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.463 |
| cls | yfhB | HMPREF0758_3528 | HMPREF0758_2466 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | HAD hydrolase, family IF; COG: COG0560; InterPro: IPR006435. | 0.909 |
| nusB | pgpA | HMPREF0758_0225 | HMPREF0758_0223 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | 0.579 |
| nusB | ribD | HMPREF0758_0225 | HMPREF0758_0227 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.732 |
| nusB | ribH | HMPREF0758_0225 | HMPREF0758_0226 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.941 |
| nusB | thiL | HMPREF0758_0225 | HMPREF0758_0224 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.624 |
| pgpA | PlcN | HMPREF0758_0223 | HMPREF0758_1988 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | 0.900 |
| pgpA | cls | HMPREF0758_0223 | HMPREF0758_3528 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.917 |
| pgpA | nusB | HMPREF0758_0223 | HMPREF0758_0225 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.579 |
| pgpA | pgpB-2 | HMPREF0758_0223 | HMPREF0758_3565 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | Phosphatidylglycerophosphatase B; COG: COG0671; Pfam: PF01569; InterPro: IPR000326. | 0.921 |
| pgpA | pgsA | HMPREF0758_0223 | HMPREF0758_4263 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.948 |
| pgpA | psd | HMPREF0758_0223 | HMPREF0758_0875 | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.412 |