| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| YicI_1 | cscA | HMPREF0758_2512 | HMPREF0758_4026 | Glycosyl hydrolase, family 31; COG: COG1501; Pfam: PF01055; InterPro: IPR000322; Belongs to the glycosyl hydrolase 31 family. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.906 |
| YicI_1 | mak | HMPREF0758_2512 | HMPREF0758_0250 | Glycosyl hydrolase, family 31; COG: COG1501; Pfam: PF01055; InterPro: IPR000322; Belongs to the glycosyl hydrolase 31 family. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.912 |
| YicI_1 | scrB | HMPREF0758_2512 | HMPREF0758_1984 | Glycosyl hydrolase, family 31; COG: COG1501; Pfam: PF01055; InterPro: IPR000322; Belongs to the glycosyl hydrolase 31 family. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.906 |
| cscA | YicI_1 | HMPREF0758_4026 | HMPREF0758_2512 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | Glycosyl hydrolase, family 31; COG: COG1501; Pfam: PF01055; InterPro: IPR000322; Belongs to the glycosyl hydrolase 31 family. | 0.906 |
| cscA | fruA | HMPREF0758_4026 | HMPREF0758_2890 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | 0.432 |
| cscA | mak | HMPREF0758_4026 | HMPREF0758_0250 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.913 |
| cscA | scrB | HMPREF0758_4026 | HMPREF0758_1984 | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.916 |
| fruA | cscA | HMPREF0758_2890 | HMPREF0758_4026 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.432 |
| fruA | mak | HMPREF0758_2890 | HMPREF0758_0250 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.939 |
| fruA | manA | HMPREF0758_2890 | HMPREF0758_3835 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.649 |
| fruA | nagB | HMPREF0758_2890 | HMPREF0758_4887 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.410 |
| fruA | pfkA | HMPREF0758_2890 | HMPREF0758_1183 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.507 |
| fruA | pgi | HMPREF0758_2890 | HMPREF0758_1693 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.529 |
| fruA | scrB | HMPREF0758_2890 | HMPREF0758_1984 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.432 |
| fruA | xylA | HMPREF0758_2890 | HMPREF0758_1434 | Phosphotransferase system, EIIC; COG: COG1299; Pfam: PF02379,PF02378; InterPro: IPR006327. | Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family. | 0.937 |
| glmS | mak | HMPREF0758_1337 | HMPREF0758_0250 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.913 |
| glmS | manA | HMPREF0758_1337 | HMPREF0758_3835 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.918 |
| glmS | nagB | HMPREF0758_1337 | HMPREF0758_4887 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.940 |
| glmS | pgi | HMPREF0758_1337 | HMPREF0758_1693 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.938 |
| mak | YicI_1 | HMPREF0758_0250 | HMPREF0758_2512 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Glycosyl hydrolase, family 31; COG: COG1501; Pfam: PF01055; InterPro: IPR000322; Belongs to the glycosyl hydrolase 31 family. | 0.912 |