| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ArgE_1 | EFE97983.1 | HMPREF0758_0312 | HMPREF0758_0311 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Hypothetical protein; COG: COG5426; Pfam: PF07090; InterPro: IPR010768. | 0.889 |
| ArgE_1 | Opd | HMPREF0758_0312 | HMPREF0758_0310 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | 0.853 |
| ArgE_1 | argA | HMPREF0758_0312 | HMPREF0758_2307 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | 0.578 |
| ArgE_1 | argB | HMPREF0758_0312 | HMPREF0758_1154 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | 0.625 |
| ArgE_1 | argC | HMPREF0758_0312 | HMPREF0758_1155 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.706 |
| ArgE_1 | argD | HMPREF0758_0312 | HMPREF0758_0999 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.918 |
| ArgE_1 | argG | HMPREF0758_0312 | HMPREF0758_1153 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.663 |
| ArgE_1 | dapE | HMPREF0758_0312 | HMPREF0758_2609 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.935 |
| ArgE_1 | dapF | HMPREF0758_0312 | HMPREF0758_1535 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.914 |
| ArgE_1 | xylG | HMPREF0758_0312 | HMPREF0758_0308 | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003593. | 0.691 |
| EFE97983.1 | ArgE_1 | HMPREF0758_0311 | HMPREF0758_0312 | Hypothetical protein; COG: COG5426; Pfam: PF07090; InterPro: IPR010768. | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | 0.889 |
| EFE97983.1 | Opd | HMPREF0758_0311 | HMPREF0758_0310 | Hypothetical protein; COG: COG5426; Pfam: PF07090; InterPro: IPR010768. | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | 0.944 |
| EFE97983.1 | xylG | HMPREF0758_0311 | HMPREF0758_0308 | Hypothetical protein; COG: COG5426; Pfam: PF07090; InterPro: IPR010768. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003593. | 0.798 |
| Opd | ArgE_1 | HMPREF0758_0310 | HMPREF0758_0312 | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | 0.853 |
| Opd | EFE97983.1 | HMPREF0758_0310 | HMPREF0758_0311 | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | Hypothetical protein; COG: COG5426; Pfam: PF07090; InterPro: IPR010768. | 0.944 |
| Opd | xylG | HMPREF0758_0310 | HMPREF0758_0308 | Phosphotriesterase family protein; COG: COG1735; Pfam: PF02126; InterPro: IPR001559. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003593. | 0.776 |
| argA | ArgE_1 | HMPREF0758_2307 | HMPREF0758_0312 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Peptidase, ArgE/DapE family; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR002933. | 0.578 |
| argA | argB | HMPREF0758_2307 | HMPREF0758_1154 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. | 0.993 |
| argA | argC | HMPREF0758_2307 | HMPREF0758_1155 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.975 |
| argA | argD | HMPREF0758_2307 | HMPREF0758_0999 | Amino-acid N-acetyltransferase; COG: COG0548; Pfam: PF00696,PF00583; InterPro: IPR010167; Belongs to the acetyltransferase family. ArgA subfamily. | Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.867 |