STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pucGAminotransferase, class V; COG: COG0075; Pfam: PF00266; InterPro: IPR000192. (413 aa)    
Predicted Functional Partners:
amaB
Allantoate amidohydrolase; COG: COG0624; Pfam: PF01546,PF07687; InterPro: IPR010158.
 
 
  0.992
gatA
Amidohydrolase, AtzE family; COG: COG0154; Pfam: PF01425; InterPro: IPR014087.
 
  0.932
uraH
Hydroxyisourate hydrolase; COG: COG2351; Pfam: PF00576; InterPro: IPR000895; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
    0.892
uraD
OHCU decarboxylase.
 
     0.885
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.884
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.882
itaE
Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597.
    
 0.865
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
    
 0.829
pbuX
Xanthine permease; COG: COG2233; Pfam: PF00860; InterPro: IPR006042.
 
    0.669
artP
ABC transporter, ATP-binding protein; COG: COG1126; Pfam: PF00005; InterPro: IPR003593.
     
 0.662
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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