| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HcaD | gloB | HMPREF0758_2186 | HMPREF0758_0373 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0446; Pfam: PF07992,PF00070; InterPro: IPR013027. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.426 |
| HcaD | gloB3 | HMPREF0758_2186 | HMPREF0758_4364 | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0446; Pfam: PF07992,PF00070; InterPro: IPR013027. | Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. | 0.426 |
| dld | gloB | HMPREF0758_4757 | HMPREF0758_0373 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.905 |
| dld | gloB3 | HMPREF0758_4757 | HMPREF0758_4364 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. | 0.903 |
| dld | pdxB-4 | HMPREF0758_4757 | HMPREF0758_3625 | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | 4-phosphoerythronate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.921 |
| dniR | gloB | HMPREF0758_0374 | HMPREF0758_0373 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.606 |
| dniR | smtA | HMPREF0758_0374 | HMPREF0758_0372 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | Methyltransferase domain protein; COG: COG0500; Pfam: PF08241. | 0.600 |
| gloA-2 | gloB | HMPREF0758_3920 | HMPREF0758_0373 | Lactoylglutathione lyase; COG: COG0346; Pfam: PF00903; InterPro: IPR004361. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.977 |
| gloA-2 | gloB3 | HMPREF0758_3920 | HMPREF0758_4364 | Lactoylglutathione lyase; COG: COG0346; Pfam: PF00903; InterPro: IPR004361. | Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. | 0.930 |
| gloA-2 | gor | HMPREF0758_3920 | HMPREF0758_1103 | Lactoylglutathione lyase; COG: COG0346; Pfam: PF00903; InterPro: IPR004361. | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | 0.511 |
| gloA-2 | grxD | HMPREF0758_3920 | HMPREF0758_3922 | Lactoylglutathione lyase; COG: COG0346; Pfam: PF00903; InterPro: IPR004361. | Monothiol glutaredoxin, Grx4 family; COG: COG0278; Pfam: PF00462; InterPro: IPR012335; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.531 |
| gloB | HcaD | HMPREF0758_0373 | HMPREF0758_2186 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Pyridine nucleotide-disulfide oxidoreductase; COG: COG0446; Pfam: PF07992,PF00070; InterPro: IPR013027. | 0.426 |
| gloB | dld | HMPREF0758_0373 | HMPREF0758_4757 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | FAD binding domain protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | 0.905 |
| gloB | dniR | HMPREF0758_0373 | HMPREF0758_0374 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | 0.606 |
| gloB | gloA-2 | HMPREF0758_0373 | HMPREF0758_3920 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Lactoylglutathione lyase; COG: COG0346; Pfam: PF00903; InterPro: IPR004361. | 0.977 |
| gloB | gloB3 | HMPREF0758_0373 | HMPREF0758_4364 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. | 0.915 |
| gloB | gor | HMPREF0758_0373 | HMPREF0758_1103 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Glutathione-disulfide reductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006322. | 0.515 |
| gloB | grxD | HMPREF0758_0373 | HMPREF0758_3922 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Monothiol glutaredoxin, Grx4 family; COG: COG0278; Pfam: PF00462; InterPro: IPR012335; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.588 |
| gloB | pdxB-4 | HMPREF0758_0373 | HMPREF0758_3625 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 4-phosphoerythronate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.909 |
| gloB | smtA | HMPREF0758_0373 | HMPREF0758_0372 | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | Methyltransferase domain protein; COG: COG0500; Pfam: PF08241. | 0.640 |