| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysA-2 | cysC | HMPREF0758_2652 | HMPREF0758_0445 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.948 |
| cysA-2 | cysD | HMPREF0758_2652 | HMPREF0758_0447 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfate adenylyltransferase, small subunit; COG: COG0175; Pfam: PF01507; InterPro: IPR011784. | 0.993 |
| cysA-2 | cysH | HMPREF0758_2652 | HMPREF0758_0450 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.950 |
| cysA-2 | cysI | HMPREF0758_2652 | HMPREF0758_0451 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.954 |
| cysA-2 | cysJ | HMPREF0758_2652 | HMPREF0758_0452 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfite reductase (NADPH) flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | 0.912 |
| cysA-2 | cysN | HMPREF0758_2652 | HMPREF0758_0446 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.996 |
| cysA-2 | cysP | HMPREF0758_2652 | HMPREF0758_2649 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfate ABC transporter, sulfate-binding protein; COG: COG4150; Pfam: PF01547; InterPro: IPR005669. | 0.999 |
| cysA-2 | cysT | HMPREF0758_2652 | HMPREF0758_2650 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.999 |
| cysA-2 | cysW | HMPREF0758_2652 | HMPREF0758_2651 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfate ABC transporter, permease protein CysW; COG: COG4208; Pfam: PF00528; InterPro: IPR005667. | 0.999 |
| cysA-2 | sbp | HMPREF0758_2652 | HMPREF0758_1182 | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | Sulfate ABC transporter, sulfate-binding protein; COG: COG1613; Pfam: PF01547; InterPro: IPR005669. | 0.998 |
| cysC | cysA-2 | HMPREF0758_0445 | HMPREF0758_2652 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.948 |
| cysC | cysD | HMPREF0758_0445 | HMPREF0758_0447 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate adenylyltransferase, small subunit; COG: COG0175; Pfam: PF01507; InterPro: IPR011784. | 0.999 |
| cysC | cysH | HMPREF0758_0445 | HMPREF0758_0450 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.997 |
| cysC | cysI | HMPREF0758_0445 | HMPREF0758_0451 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.963 |
| cysC | cysJ | HMPREF0758_0445 | HMPREF0758_0452 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfite reductase (NADPH) flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | 0.943 |
| cysC | cysN | HMPREF0758_0445 | HMPREF0758_0446 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysC | cysP | HMPREF0758_0445 | HMPREF0758_2649 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate ABC transporter, sulfate-binding protein; COG: COG4150; Pfam: PF01547; InterPro: IPR005669. | 0.910 |
| cysC | cysT | HMPREF0758_0445 | HMPREF0758_2650 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.844 |
| cysC | cysW | HMPREF0758_0445 | HMPREF0758_2651 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate ABC transporter, permease protein CysW; COG: COG4208; Pfam: PF00528; InterPro: IPR005667. | 0.953 |
| cysC | sbp | HMPREF0758_0445 | HMPREF0758_1182 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate ABC transporter, sulfate-binding protein; COG: COG1613; Pfam: PF01547; InterPro: IPR005669. | 0.876 |