| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FeuC | btuD | HMPREF0758_1620 | HMPREF0758_3973 | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | 0.536 |
| FeuC | btuF | HMPREF0758_1620 | HMPREF0758_0489 | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.863 |
| FeuC | fhuC | HMPREF0758_1620 | HMPREF0758_2170 | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | 0.905 |
| FeuC | fhuC2 | HMPREF0758_1620 | HMPREF0758_2677 | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | 0.905 |
| YadS | btuF | HMPREF0758_0490 | HMPREF0758_0489 | Hypothetical protein; COG: COG2860; Pfam: PF03458; InterPro: IPR005115. | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.815 |
| YadS | mtnN | HMPREF0758_0490 | HMPREF0758_0488 | Hypothetical protein; COG: COG2860; Pfam: PF03458; InterPro: IPR005115. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylas [...] | 0.801 |
| btuC | btuD | HMPREF0758_3975 | HMPREF0758_3973 | Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | 0.998 |
| btuC | btuF | HMPREF0758_3975 | HMPREF0758_0489 | Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.994 |
| btuC | fhuC | HMPREF0758_3975 | HMPREF0758_2170 | Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | 0.793 |
| btuC | fhuC2 | HMPREF0758_3975 | HMPREF0758_2677 | Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. | ABC transporter, ATP-binding protein; COG: COG1120; Pfam: PF00005; InterPro: IPR003593. | 0.776 |
| btuD | FeuC | HMPREF0758_3973 | HMPREF0758_1620 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.536 |
| btuD | btuC | HMPREF0758_3973 | HMPREF0758_3975 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. | 0.998 |
| btuD | btuF | HMPREF0758_3973 | HMPREF0758_0489 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | 0.940 |
| btuD | fepD | HMPREF0758_3973 | HMPREF0758_2679 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.479 |
| btuD | hemU | HMPREF0758_3973 | HMPREF0758_2897 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Gram-positive signal peptide protein, YSIRK family; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.588 |
| btuD | hmuU | HMPREF0758_3973 | HMPREF0758_3958 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.596 |
| btuF | FeuC | HMPREF0758_0489 | HMPREF0758_1620 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609; Pfam: PF01032; InterPro: IPR000522; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.863 |
| btuF | YadS | HMPREF0758_0489 | HMPREF0758_0490 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | Hypothetical protein; COG: COG2860; Pfam: PF03458; InterPro: IPR005115. | 0.815 |
| btuF | btuC | HMPREF0758_0489 | HMPREF0758_3975 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | Iron chelate uptake ABC transporter, FeCT family, permease protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. | 0.994 |
| btuF | btuD | HMPREF0758_0489 | HMPREF0758_3973 | Periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. | 0.940 |