| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gspO | hofC | HMPREF0758_2035 | HMPREF0758_0498 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | 0.764 |
| gspO | ispE | HMPREF0758_2035 | HMPREF0758_2117 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Twitching motility protein; COG: COG2805; Pfam: PF00437; InterPro: IPR006321. | 0.618 |
| gspO | pilB | HMPREF0758_2035 | HMPREF0758_0497 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Type II/IV secretion system protein; COG: COG2804; Pfam: PF00437; InterPro: IPR001482. | 0.708 |
| gspO | pilQ | HMPREF0758_2035 | HMPREF0758_1026 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Type IV pilus secretin PilQ; COG: COG4796; Pfam: PF07660,PF03958,PF00263; InterPro: IPR013355. | 0.664 |
| gspO | ppdA | HMPREF0758_2035 | HMPREF0758_2299 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG2165; Pfam: PF07963. | 0.437 |
| gspO | ppdD | HMPREF0758_2035 | HMPREF0758_0496 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG4969; Pfam: PF07963; InterPro: IPR001082; Belongs to the N-Me-Phe pilin family. | 0.464 |
| gspO | rec | HMPREF0758_2035 | HMPREF0758_4381 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.747 |
| gspO | topA | HMPREF0758_2035 | HMPREF0758_0196 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Competence protein ComEA helix-hairpin-helix repeat region; COG: COG1555; InterPro: IPR004509. | 0.601 |
| gspO | traN | HMPREF0758_2035 | HMPREF0758_5037 | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | type-F conjugative transfer system mating-pair stabilization protein TraN; Pfam: PF06986; InterPro: IPR014121. | 0.437 |
| gspO2 | hofC | HMPREF0758_3259 | HMPREF0758_0498 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | 0.764 |
| gspO2 | ispE | HMPREF0758_3259 | HMPREF0758_2117 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Twitching motility protein; COG: COG2805; Pfam: PF00437; InterPro: IPR006321. | 0.591 |
| gspO2 | pilB | HMPREF0758_3259 | HMPREF0758_0497 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Type II/IV secretion system protein; COG: COG2804; Pfam: PF00437; InterPro: IPR001482. | 0.731 |
| gspO2 | pilQ | HMPREF0758_3259 | HMPREF0758_1026 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Type IV pilus secretin PilQ; COG: COG4796; Pfam: PF07660,PF03958,PF00263; InterPro: IPR013355. | 0.591 |
| gspO2 | ppdA | HMPREF0758_3259 | HMPREF0758_2299 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Prepilin-type cleavage/methylation N-terminal domain protein; COG: COG2165; Pfam: PF07963. | 0.437 |
| gspO2 | rec | HMPREF0758_3259 | HMPREF0758_4381 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.745 |
| gspO2 | topA | HMPREF0758_3259 | HMPREF0758_0196 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | Competence protein ComEA helix-hairpin-helix repeat region; COG: COG1555; InterPro: IPR004509. | 0.601 |
| gspO2 | traN | HMPREF0758_3259 | HMPREF0758_5037 | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | type-F conjugative transfer system mating-pair stabilization protein TraN; Pfam: PF06986; InterPro: IPR014121. | 0.437 |
| hofC | gspO | HMPREF0758_0498 | HMPREF0758_2035 | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | Type 4 prepilin-like protein leader peptide-processing enzyme domain protein; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | 0.764 |
| hofC | gspO2 | HMPREF0758_0498 | HMPREF0758_3259 | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | Peptidase, A24 family; COG: COG1989; Pfam: PF01478; InterPro: IPR000045; Belongs to the peptidase A24 family. | 0.764 |
| hofC | ispE | HMPREF0758_0498 | HMPREF0758_2117 | Bacterial type II secretion system domain protein F; COG: COG1459; Pfam: PF00482; InterPro: IPR001992. | Twitching motility protein; COG: COG2805; Pfam: PF00437; InterPro: IPR006321. | 0.964 |