| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE97935.1 | ftsI | HMPREF0758_0519 | HMPREF0758_0520 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | 0.990 |
| EFE97935.1 | ftsQ | HMPREF0758_0519 | HMPREF0758_0510 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.833 |
| EFE97935.1 | ftsW | HMPREF0758_0519 | HMPREF0758_0514 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.946 |
| EFE97935.1 | mrdB | HMPREF0758_0519 | HMPREF0758_4917 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.820 |
| EFE97935.1 | murC | HMPREF0758_0519 | HMPREF0758_0512 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.766 |
| EFE97935.1 | murD | HMPREF0758_0519 | HMPREF0758_0515 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.842 |
| EFE97935.1 | murE | HMPREF0758_0519 | HMPREF0758_0518 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.922 |
| EFE97935.1 | murF | HMPREF0758_0519 | HMPREF0758_0517 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.846 |
| EFE97935.1 | murG | HMPREF0758_0519 | HMPREF0758_0513 | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.806 |
| ftsI | EFE97935.1 | HMPREF0758_0520 | HMPREF0758_0519 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Hypothetical protein; COG: COG0768; Pfam: PF00905; InterPro: IPR001460; 2.4.1.129. | 0.990 |
| ftsI | ftsI2 | HMPREF0758_0520 | HMPREF0758_3674 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Penicillin-binding protein, transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.908 |
| ftsI | ftsQ | HMPREF0758_0520 | HMPREF0758_0510 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.864 |
| ftsI | ftsW | HMPREF0758_0520 | HMPREF0758_0514 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.961 |
| ftsI | mrdB | HMPREF0758_0520 | HMPREF0758_4917 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.855 |
| ftsI | murC | HMPREF0758_0520 | HMPREF0758_0512 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.860 |
| ftsI | murD | HMPREF0758_0520 | HMPREF0758_0515 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.871 |
| ftsI | murE | HMPREF0758_0520 | HMPREF0758_0518 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.954 |
| ftsI | murF | HMPREF0758_0520 | HMPREF0758_0517 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.903 |
| ftsI | murG | HMPREF0758_0520 | HMPREF0758_0513 | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.859 |
| ftsI2 | ftsI | HMPREF0758_3674 | HMPREF0758_0520 | Penicillin-binding protein, transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein dimerization domain protein; COG: COG0768; Pfam: PF03717,PF00905; InterPro: IPR005311. | 0.908 |