| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysA | eno | HMPREF0758_0541 | HMPREF0758_0472 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.473 |
| cysA | ksgA | HMPREF0758_0541 | HMPREF0758_0553 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.571 |
| cysA | rplE | HMPREF0758_0541 | HMPREF0758_0949 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.442 |
| cysA | rpsE | HMPREF0758_0541 | HMPREF0758_0944 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.605 |
| cysA | rpsK | HMPREF0758_0541 | HMPREF0758_0939 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.619 |
| cysA | serS | HMPREF0758_0541 | HMPREF0758_4447 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.451 |
| cysA | thiB | HMPREF0758_0541 | HMPREF0758_0539 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | Thiamine/thiamine pyrophosphate ABC transporter, thiamine/thiamine pyrophospate-binding protein; COG: COG4143; Pfam: PF01547; InterPro: IPR005967. | 0.969 |
| cysA | thiP | HMPREF0758_0541 | HMPREF0758_0540 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | Thiamine/thiamine pyrophosphate ABC transporter, permease protein; COG: COG1178; Pfam: PF00528; InterPro: IPR005947. | 0.978 |
| cysA | xylG | HMPREF0758_0541 | HMPREF0758_0308 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | ABC transporter, ATP-binding protein; COG: COG1129; Pfam: PF00005; InterPro: IPR003593. | 0.556 |
| cysA | znuC | HMPREF0758_0541 | HMPREF0758_3430 | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | High-affinity zinc transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. | 0.430 |
| eno | cysA | HMPREF0758_0472 | HMPREF0758_0541 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | 0.473 |
| eno | ksgA | HMPREF0758_0472 | HMPREF0758_0553 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.478 |
| eno | rplE | HMPREF0758_0472 | HMPREF0758_0949 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.576 |
| eno | rpsE | HMPREF0758_0472 | HMPREF0758_0944 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.882 |
| eno | rpsK | HMPREF0758_0472 | HMPREF0758_0939 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.866 |
| eno | serS | HMPREF0758_0472 | HMPREF0758_4447 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.548 |
| ksgA | cysA | HMPREF0758_0553 | HMPREF0758_0541 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | ABC transporter, ATP-binding protein; COG: COG3840; Pfam: PF00005; InterPro: IPR003439. | 0.571 |
| ksgA | eno | HMPREF0758_0553 | HMPREF0758_0472 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.478 |
| ksgA | rplE | HMPREF0758_0553 | HMPREF0758_0949 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.410 |
| ksgA | rpsE | HMPREF0758_0553 | HMPREF0758_0944 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.905 |