| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE97669.1 | FkpB | HMPREF0758_0576 | HMPREF0758_0572 | Hypothetical protein; 3.1.26.5. | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | 0.445 |
| EFE97669.1 | ileS | HMPREF0758_0576 | HMPREF0758_0574 | Hypothetical protein; 3.1.26.5. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.445 |
| EFE97669.1 | ispH | HMPREF0758_0576 | HMPREF0758_0571 | Hypothetical protein; 3.1.26.5. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | 0.445 |
| EFE97669.1 | lspA | HMPREF0758_0576 | HMPREF0758_0573 | Hypothetical protein; 3.1.26.5. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.445 |
| EFE97669.1 | ribF | HMPREF0758_0576 | HMPREF0758_0575 | Hypothetical protein; 3.1.26.5. | Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family. | 0.501 |
| EFE97669.1 | rpsT | HMPREF0758_0576 | HMPREF0758_0577 | Hypothetical protein; 3.1.26.5. | Ribosomal protein S20; COG: COG0268; Pfam: PF01649; InterPro: IPR002583. | 0.488 |
| FkpB | EFE97669.1 | HMPREF0758_0572 | HMPREF0758_0576 | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | Hypothetical protein; 3.1.26.5. | 0.445 |
| FkpB | ileS | HMPREF0758_0572 | HMPREF0758_0574 | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.827 |
| FkpB | ispH | HMPREF0758_0572 | HMPREF0758_0571 | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | 0.907 |
| FkpB | lspA | HMPREF0758_0572 | HMPREF0758_0573 | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.879 |
| FkpB | ribF | HMPREF0758_0572 | HMPREF0758_0575 | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family. | 0.711 |
| ileS | EFE97669.1 | HMPREF0758_0574 | HMPREF0758_0576 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Hypothetical protein; 3.1.26.5. | 0.445 |
| ileS | FkpB | HMPREF0758_0574 | HMPREF0758_0572 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | 0.827 |
| ileS | ispH | HMPREF0758_0574 | HMPREF0758_0571 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | 0.798 |
| ileS | lspA | HMPREF0758_0574 | HMPREF0758_0573 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.920 |
| ileS | ribF | HMPREF0758_0574 | HMPREF0758_0575 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family. | 0.727 |
| ileS | rpsT | HMPREF0758_0574 | HMPREF0758_0577 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Ribosomal protein S20; COG: COG0268; Pfam: PF01649; InterPro: IPR002583. | 0.436 |
| ispH | EFE97669.1 | HMPREF0758_0571 | HMPREF0758_0576 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | Hypothetical protein; 3.1.26.5. | 0.445 |
| ispH | FkpB | HMPREF0758_0571 | HMPREF0758_0572 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG: COG1047; Pfam: PF00254; InterPro: IPR001179. | 0.907 |
| ispH | ileS | HMPREF0758_0571 | HMPREF0758_0574 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.798 |