STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpRTrp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (113 aa)    
Predicted Functional Partners:
EFE96731.1
Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525.
  
    0.812
lepB
Signal peptidase I; COG: COG0681; Pfam: PF00717; InterPro: IPR011056; Belongs to the peptidase S26 family.
   
    0.790
matP
Hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.770
torD
Cytoplasmic chaperone TorD; COG: COG3381; Pfam: PF06192; InterPro: IPR010395.
  
    0.745
slt
Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF01464; InterPro: IPR008939.
 
     0.733
EFE94900.1
Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family.
  
     0.718
EFE96208.1
Hypothetical protein; COG: COG3112; Pfam: PF06062; InterPro: IPR008249; Belongs to the UPF0231 family.
  
     0.698
EFE96176.1
Hypothetical protein.
  
     0.687
mukF
KicB killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.677
EFE94427.1
Hypothetical protein.
  
     0.669
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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