| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE97270.1 | YfkN_1 | HMPREF0758_1098 | HMPREF0758_0617 | Hypothetical protein; InterPro: IPR006179; overlaps another CDS with the same product name; 3.1.4.16. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.576 |
| NadR_1 | YfkN_1 | HMPREF0758_0608 | HMPREF0758_0617 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.557 |
| NadR_1 | deoD | HMPREF0758_0608 | HMPREF0758_0612 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.917 |
| NadR_1 | nudC | HMPREF0758_0608 | HMPREF0758_1672 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | NAD(+) diphosphatase; COG: COG2816; Pfam: PF09296,PF09297,PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.905 |
| YfkN_1 | EFE97270.1 | HMPREF0758_0617 | HMPREF0758_1098 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Hypothetical protein; InterPro: IPR006179; overlaps another CDS with the same product name; 3.1.4.16. | 0.576 |
| YfkN_1 | NadR_1 | HMPREF0758_0617 | HMPREF0758_0608 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | 0.557 |
| YfkN_1 | add | HMPREF0758_0617 | HMPREF0758_3853 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 0.559 |
| YfkN_1 | deoC | HMPREF0758_0617 | HMPREF0758_0615 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | 0.422 |
| YfkN_1 | deoD | HMPREF0758_0617 | HMPREF0758_0612 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.570 |
| YfkN_1 | guaB | HMPREF0758_0617 | HMPREF0758_2514 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.518 |
| YfkN_1 | nudC | HMPREF0758_0617 | HMPREF0758_1672 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | NAD(+) diphosphatase; COG: COG2816; Pfam: PF09296,PF09297,PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudC subfamily. | 0.518 |
| YfkN_1 | nupC | HMPREF0758_0617 | HMPREF0758_0616 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Nucleoside transporter, NupC family; COG: COG1972; Pfam: PF01773,PF07670,PF07662; InterPro: IPR008276; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | 0.482 |
| YfkN_1 | ppnP | HMPREF0758_0617 | HMPREF0758_0252 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.499 |
| YfkN_1 | udk | HMPREF0758_0617 | HMPREF0758_4577 | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.402 |
| add | YfkN_1 | HMPREF0758_3853 | HMPREF0758_0617 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.559 |
| add | deoD | HMPREF0758_3853 | HMPREF0758_0612 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.914 |
| add | ppnP | HMPREF0758_3853 | HMPREF0758_0252 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.902 |
| deoC | YfkN_1 | HMPREF0758_0615 | HMPREF0758_0617 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.422 |
| deoC | deoD | HMPREF0758_0615 | HMPREF0758_0612 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.786 |
| deoC | nupC | HMPREF0758_0615 | HMPREF0758_0616 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. | Nucleoside transporter, NupC family; COG: COG1972; Pfam: PF01773,PF07670,PF07662; InterPro: IPR008276; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. | 0.517 |