| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cgtA | rsmC | HMPREF0758_0817 | HMPREF0758_0634 | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.517 |
| holD | rimI | HMPREF0758_0633 | HMPREF0758_0632 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.901 |
| holD | rsmC | HMPREF0758_0633 | HMPREF0758_0634 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.440 |
| rimI | holD | HMPREF0758_0632 | HMPREF0758_0633 | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.901 |
| rimI | rsmC | HMPREF0758_0632 | HMPREF0758_0634 | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.420 |
| rlmL | rsmC | HMPREF0758_4349 | HMPREF0758_0634 | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.461 |
| rlmL | rsmF | HMPREF0758_4349 | HMPREF0758_4017 | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.649 |
| rlmL | uppS | HMPREF0758_4349 | HMPREF0758_2336 | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.645 |
| rsmC | cgtA | HMPREF0758_0634 | HMPREF0758_0817 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.517 |
| rsmC | holD | HMPREF0758_0634 | HMPREF0758_0633 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.440 |
| rsmC | rimI | HMPREF0758_0634 | HMPREF0758_0632 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.420 |
| rsmC | rlmL | HMPREF0758_0634 | HMPREF0758_4349 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.461 |
| rsmC | rsmF | HMPREF0758_0634 | HMPREF0758_4017 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.427 |
| rsmC | tdk | HMPREF0758_0634 | HMPREF0758_3516 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | Thymidine kinase; COG: COG1435; Pfam: PF00265; InterPro: IPR001267. | 0.417 |
| rsmC | tusD | HMPREF0758_0634 | HMPREF0758_0971 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | Sulfur relay protein TusD/DsrE; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 0.444 |
| rsmC | uppS | HMPREF0758_0634 | HMPREF0758_2336 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.404 |
| rsmC | ycgL | HMPREF0758_0634 | HMPREF0758_3460 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | YcgL domain protein; COG: COG3100; Pfam: PF05166; InterPro: IPR007840. | 0.456 |
| rsmC | yhgI | HMPREF0758_0634 | HMPREF0758_1052 | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.463 |
| rsmF | rlmL | HMPREF0758_4017 | HMPREF0758_4349 | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.649 |
| rsmF | rsmC | HMPREF0758_4017 | HMPREF0758_0634 | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | Methyltransferase small domain protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. | 0.427 |