STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaD3,4-dihydroxyphenylacetate 2,3-dioxygenase; COG: COG3384; Pfam: PF02900; InterPro: IPR011984. (285 aa)    
Predicted Functional Partners:
hpcD
5-carboxymethyl-2-hydroxymuconate delta isomerase; COG: COG3232; Pfam: PF02962; InterPro: IPR014347.
 
  
 0.991
hpaH
2-oxo-hepta-3-ene-1,7-dioic acid hydratase; COG: COG3971; Pfam: PF01689; InterPro: IPR012690.
 
  
 0.983
hpaB
4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; COG: COG2368; Pfam: PF03241; InterPro: IPR012688.
 
 
 0.962
hpaA
4-hydroxyphenylacetate catabolism regulatory protein HpaA; COG: COG2207; Pfam: PF02311,PF00165; InterPro: IPR011983.
 
  
 0.950
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; COG: COG3836; Pfam: PF03328; InterPro: IPR015813; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.948
hpaC
4-hydroxyphenylacetate 3-monooxygenase, reductase component; COG: COG1853; Pfam: PF01613; InterPro: IPR002563.
 
 
 0.943
hpaG-2
4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; COG: COG0179; Pfam: PF01557; InterPro: IPR011234.
 
  
 0.881
hpaE
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; COG: COG1012; Pfam: PF00171; InterPro: IPR011985; Belongs to the aldehyde dehydrogenase family.
 
 
 0.880
hpaG
4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; COG: COG0179; Pfam: PF01557; InterPro: IPR012684.
 
  
 0.865
hpaR
Homoprotocatechuate degradation operon regulator, HpaR; COG: COG1846; Pfam: PF01047; InterPro: IPR012712.
 
   
 0.851
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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