| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cls_1 | ExbB_1 | HMPREF0758_0663 | HMPREF0758_0664 | Phospholipase D domain protein; Pfam: PF00614,PF08371. | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | 0.666 |
| Cls_1 | ExbD_1 | HMPREF0758_0663 | HMPREF0758_0667 | Phospholipase D domain protein; Pfam: PF00614,PF08371. | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | 0.524 |
| Cls_1 | FecA_1 | HMPREF0758_0663 | HMPREF0758_0665 | Phospholipase D domain protein; Pfam: PF00614,PF08371. | TonB-dependent receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR000531. | 0.623 |
| Cls_1 | tonB | HMPREF0758_0663 | HMPREF0758_0666 | Phospholipase D domain protein; Pfam: PF00614,PF08371. | TonB family domain protein. | 0.531 |
| ExbB_1 | Cls_1 | HMPREF0758_0664 | HMPREF0758_0663 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | Phospholipase D domain protein; Pfam: PF00614,PF08371. | 0.666 |
| ExbB_1 | ExbD_1 | HMPREF0758_0664 | HMPREF0758_0667 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | 0.969 |
| ExbB_1 | FecA_1 | HMPREF0758_0664 | HMPREF0758_0665 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB-dependent receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR000531. | 0.833 |
| ExbB_1 | TonB | HMPREF0758_0664 | HMPREF0758_3534 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.671 |
| ExbB_1 | exbD | HMPREF0758_0664 | HMPREF0758_1982 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB system transport protein ExbD; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | 0.874 |
| ExbB_1 | lptB | HMPREF0758_0664 | HMPREF0758_1852 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | ABC transporter, ATP-binding protein; COG: COG1137; Pfam: PF00005; InterPro: IPR003593. | 0.761 |
| ExbB_1 | lpxA | HMPREF0758_0664 | HMPREF0758_2343 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.735 |
| ExbB_1 | lpxD | HMPREF0758_0664 | HMPREF0758_2341 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.640 |
| ExbB_1 | tolR | HMPREF0758_0664 | HMPREF0758_4833 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | Putative protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.800 |
| ExbB_1 | tonB | HMPREF0758_0664 | HMPREF0758_0666 | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | TonB family domain protein. | 0.891 |
| ExbD_1 | Cls_1 | HMPREF0758_0667 | HMPREF0758_0663 | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | Phospholipase D domain protein; Pfam: PF00614,PF08371. | 0.524 |
| ExbD_1 | ExbB_1 | HMPREF0758_0667 | HMPREF0758_0664 | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | Transporter, MotA/TolQ/ExbB proton channel family protein; COG: COG0811; Pfam: PF01618; InterPro: IPR002898. | 0.969 |
| ExbD_1 | FecA_1 | HMPREF0758_0667 | HMPREF0758_0665 | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | TonB-dependent receptor; COG: COG1629; Pfam: PF07715,PF00593; InterPro: IPR000531. | 0.780 |
| ExbD_1 | TonB | HMPREF0758_0667 | HMPREF0758_3534 | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.878 |
| ExbD_1 | lptB | HMPREF0758_0667 | HMPREF0758_1852 | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | ABC transporter, ATP-binding protein; COG: COG1137; Pfam: PF00005; InterPro: IPR003593. | 0.465 |
| ExbD_1 | tonB | HMPREF0758_0667 | HMPREF0758_0666 | Transport energizing protein, ExbD/TolR family; COG: COG0848; Pfam: PF02472; InterPro: IPR003400. | TonB family domain protein. | 0.949 |