| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | carB | HMPREF0758_0566 | HMPREF0758_0565 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | 0.999 |
| carA | glmS | HMPREF0758_0566 | HMPREF0758_1337 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.926 |
| carA | glnA | HMPREF0758_0566 | HMPREF0758_0683 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | 0.927 |
| carA | glnA-2 | HMPREF0758_0566 | HMPREF0758_1297 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | Glutamine synthetase, type I; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR004809. | 0.935 |
| carA | gltB | HMPREF0758_0566 | HMPREF0758_1877 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.921 |
| carA | gltD | HMPREF0758_0566 | HMPREF0758_1876 | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | Glutamate synthase subunit beta; COG: COG0493; Pfam: PF07992,PF00070; InterPro: IPR006006. | 0.906 |
| carB | carA | HMPREF0758_0565 | HMPREF0758_0566 | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | 0.999 |
| carB | glmS | HMPREF0758_0565 | HMPREF0758_1337 | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.943 |
| carB | glnA | HMPREF0758_0565 | HMPREF0758_0683 | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | 0.925 |
| carB | glnA-2 | HMPREF0758_0565 | HMPREF0758_1297 | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | Glutamine synthetase, type I; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR004809. | 0.929 |
| carB | gltB | HMPREF0758_0565 | HMPREF0758_1877 | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.968 |
| carB | gltD | HMPREF0758_0565 | HMPREF0758_1876 | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | Glutamate synthase subunit beta; COG: COG0493; Pfam: PF07992,PF00070; InterPro: IPR006006. | 0.917 |
| gdhA | glnA | HMPREF0758_1090 | HMPREF0758_0683 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate--ammonia ligase, catalytic domain protein; COG: COG0174; Pfam: PF00120; InterPro: IPR014746; Belongs to the glutamine synthetase family. | 0.913 |
| gdhA | glnA-2 | HMPREF0758_1090 | HMPREF0758_1297 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamine synthetase, type I; COG: COG0174; Pfam: PF03951,PF00120; InterPro: IPR004809. | 0.913 |
| gdhA | gltB | HMPREF0758_1090 | HMPREF0758_1877 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.997 |
| gdhA | gltD | HMPREF0758_1090 | HMPREF0758_1876 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate synthase subunit beta; COG: COG0493; Pfam: PF07992,PF00070; InterPro: IPR006006. | 0.948 |
| gdhA | nirB-2 | HMPREF0758_1090 | HMPREF0758_3251 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Nitrite reductase [NAD(P)H], large subunit; COG: COG1251; Pfam: PF07992,PF00070,PF04324,PF03460,PF01077; InterPro: IPR012744; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.919 |
| gdhA | putA | HMPREF0758_1090 | HMPREF0758_3240 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.963 |
| gdhA | puuD | HMPREF0758_1090 | HMPREF0758_4043 | Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; COG: COG0334; Pfam: PF02812,PF00208; InterPro: IPR006095; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Gamma-glutamyl-gamma-aminobutyrate hydrolase; COG: COG2071; Pfam: PF07722; InterPro: IPR011697. | 0.800 |
| glmS | carA | HMPREF0758_1337 | HMPREF0758_0566 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | 0.926 |