| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MlaE_1 | lptB | HMPREF0758_1860 | HMPREF0758_1852 | Hypothetical protein; COG: COG0767; Pfam: PF02405; InterPro: IPR003453. | ABC transporter, ATP-binding protein; COG: COG1137; Pfam: PF00005; InterPro: IPR003593. | 0.674 |
| MlaE_1 | lptC | HMPREF0758_1860 | HMPREF0758_1854 | Hypothetical protein; COG: COG0767; Pfam: PF02405; InterPro: IPR003453. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.449 |
| MlaE_1 | lptG | HMPREF0758_1860 | HMPREF0758_0743 | Hypothetical protein; COG: COG0767; Pfam: PF02405; InterPro: IPR003453. | Lipopolysaccharide export system permease protein LptG; COG: COG0795; Pfam: PF03739; InterPro: IPR005495. | 0.590 |
| MlaE_1 | tolQ | HMPREF0758_1860 | HMPREF0758_4834 | Hypothetical protein; COG: COG0767; Pfam: PF02405; InterPro: IPR003453. | Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.410 |
| MlaE_1 | yjgP | HMPREF0758_1860 | HMPREF0758_0744 | Hypothetical protein; COG: COG0767; Pfam: PF02405; InterPro: IPR003453. | Permease, YjgP/YjgQ family; COG: COG0795; Pfam: PF03739; InterPro: IPR005495. | 0.583 |
| holC | lptC | HMPREF0758_0746 | HMPREF0758_1854 | DNA polymerase III subunit chi; COG: COG2927; Pfam: PF04364; InterPro: IPR007459. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.627 |
| holC | lptD | HMPREF0758_0746 | HMPREF0758_0550 | DNA polymerase III subunit chi; COG: COG2927; Pfam: PF04364; InterPro: IPR007459. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.651 |
| holC | lptG | HMPREF0758_0746 | HMPREF0758_0743 | DNA polymerase III subunit chi; COG: COG2927; Pfam: PF04364; InterPro: IPR007459. | Lipopolysaccharide export system permease protein LptG; COG: COG0795; Pfam: PF03739; InterPro: IPR005495. | 0.552 |
| holC | yjgP | HMPREF0758_0746 | HMPREF0758_0744 | DNA polymerase III subunit chi; COG: COG2927; Pfam: PF04364; InterPro: IPR007459. | Permease, YjgP/YjgQ family; COG: COG0795; Pfam: PF03739; InterPro: IPR005495. | 0.615 |
| lolA | lolB | HMPREF0758_4449 | HMPREF0758_3390 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.714 |
| lolA | lptC | HMPREF0758_4449 | HMPREF0758_1854 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.533 |
| lolA | lptD | HMPREF0758_4449 | HMPREF0758_0550 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.790 |
| lolA | yaeT | HMPREF0758_4449 | HMPREF0758_2339 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | 0.774 |
| lolA | yjgP | HMPREF0758_4449 | HMPREF0758_0744 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Permease, YjgP/YjgQ family; COG: COG0795; Pfam: PF03739; InterPro: IPR005495. | 0.608 |
| lolB | lolA | HMPREF0758_3390 | HMPREF0758_4449 | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.714 |
| lolB | lptC | HMPREF0758_3390 | HMPREF0758_1854 | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.548 |
| lolB | lptD | HMPREF0758_3390 | HMPREF0758_0550 | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. | 0.581 |
| lolB | yjgP | HMPREF0758_3390 | HMPREF0758_0744 | Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | Permease, YjgP/YjgQ family; COG: COG0795; Pfam: PF03739; InterPro: IPR005495. | 0.617 |
| lptB | MlaE_1 | HMPREF0758_1852 | HMPREF0758_1860 | ABC transporter, ATP-binding protein; COG: COG1137; Pfam: PF00005; InterPro: IPR003593. | Hypothetical protein; COG: COG0767; Pfam: PF02405; InterPro: IPR003453. | 0.674 |
| lptB | lptC | HMPREF0758_1852 | HMPREF0758_1854 | ABC transporter, ATP-binding protein; COG: COG1137; Pfam: PF00005; InterPro: IPR003593. | Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.999 |