| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ansA | argG | HMPREF0758_3497 | HMPREF0758_1153 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.908 |
| ansA | asnA | HMPREF0758_3497 | HMPREF0758_1321 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Aspartate--ammonia ligase; COG: COG2502; Pfam: PF03590; InterPro: IPR004618. | 0.900 |
| ansA | asnB | HMPREF0758_3497 | HMPREF0758_4893 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Asparagine synthase (glutamine-hydrolyzing); COG: COG0367; Pfam: PF00310,PF00733; InterPro: IPR006426. | 0.924 |
| ansA | aspA | HMPREF0758_3497 | HMPREF0758_0894 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.955 |
| ansA | purA | HMPREF0758_3497 | HMPREF0758_0859 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.900 |
| ansA | pyrB | HMPREF0758_3497 | HMPREF0758_0752 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.911 |
| ansA | pyrI | HMPREF0758_3497 | HMPREF0758_0753 | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.912 |
| argG | ansA | HMPREF0758_1153 | HMPREF0758_3497 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | 0.908 |
| argG | asnA | HMPREF0758_1153 | HMPREF0758_1321 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate--ammonia ligase; COG: COG2502; Pfam: PF03590; InterPro: IPR004618. | 0.903 |
| argG | asnB | HMPREF0758_1153 | HMPREF0758_4893 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Asparagine synthase (glutamine-hydrolyzing); COG: COG0367; Pfam: PF00310,PF00733; InterPro: IPR006426. | 0.923 |
| argG | aspA | HMPREF0758_1153 | HMPREF0758_0894 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.827 |
| argG | carA | HMPREF0758_1153 | HMPREF0758_0566 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamoyl-phosphate synthase, small subunit; COG: COG0505; Pfam: PF00988,PF00117; InterPro: IPR006274; Belongs to the CarA family. | 0.941 |
| argG | carB | HMPREF0758_1153 | HMPREF0758_0565 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Pfam: PF00289,PF02786,PF02787,PF02142; InterPro: IPR006275; Belongs to the CarB family. | 0.994 |
| argG | purA | HMPREF0758_1153 | HMPREF0758_0859 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.939 |
| argG | pyrB | HMPREF0758_1153 | HMPREF0758_0752 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase; COG: COG0540; Pfam: PF02729,PF00185; InterPro: IPR002082; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.908 |
| argG | pyrI | HMPREF0758_1153 | HMPREF0758_0753 | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.900 |
| asnA | ansA | HMPREF0758_1321 | HMPREF0758_3497 | Aspartate--ammonia ligase; COG: COG2502; Pfam: PF03590; InterPro: IPR004618. | L-asparaginase, type I; COG: COG0252; Pfam: PF00710; InterPro: IPR006033. | 0.900 |
| asnA | argG | HMPREF0758_1321 | HMPREF0758_1153 | Aspartate--ammonia ligase; COG: COG2502; Pfam: PF03590; InterPro: IPR004618. | Argininosuccinate synthase; COG: COG0137; Pfam: PF00764; InterPro: IPR001518; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.903 |
| asnA | asnB | HMPREF0758_1321 | HMPREF0758_4893 | Aspartate--ammonia ligase; COG: COG2502; Pfam: PF03590; InterPro: IPR004618. | Asparagine synthase (glutamine-hydrolyzing); COG: COG0367; Pfam: PF00310,PF00733; InterPro: IPR006426. | 0.922 |
| asnA | aspA | HMPREF0758_1321 | HMPREF0758_0894 | Aspartate--ammonia ligase; COG: COG2502; Pfam: PF03590; InterPro: IPR004618. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.900 |