| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE95393.1 | hcr | HMPREF0758_3084 | HMPREF0758_4466 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.601 |
| EFE95393.1 | hmpA | HMPREF0758_3084 | HMPREF0758_2477 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.923 |
| EFE95393.1 | paaK | HMPREF0758_3084 | HMPREF0758_3095 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | phenylacetate-CoA oxygenase/reductase, PaaK subunit; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR011884. | 0.731 |
| EFE95393.1 | ric | HMPREF0758_3084 | HMPREF0758_0843 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.454 |
| EFE95393.1 | rubA | HMPREF0758_3084 | HMPREF0758_0910 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Rubredoxin; COG: COG1773; Pfam: PF00301; InterPro: IPR004039; Belongs to the rubredoxin family. | 0.664 |
| cpdB | ric | HMPREF0758_0842 | HMPREF0758_0843 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.518 |
| hcr | EFE95393.1 | HMPREF0758_4466 | HMPREF0758_3084 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 0.601 |
| hcr | hmpA | HMPREF0758_4466 | HMPREF0758_2477 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.455 |
| hcr | nsrR | HMPREF0758_4466 | HMPREF0758_0858 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | 0.436 |
| hcr | ric | HMPREF0758_4466 | HMPREF0758_0843 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.488 |
| hcr | rubA | HMPREF0758_4466 | HMPREF0758_0910 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | Rubredoxin; COG: COG1773; Pfam: PF00301; InterPro: IPR004039; Belongs to the rubredoxin family. | 0.621 |
| hmpA | EFE95393.1 | HMPREF0758_2477 | HMPREF0758_3084 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | 0.923 |
| hmpA | hcr | HMPREF0758_2477 | HMPREF0758_4466 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.455 |
| hmpA | nsrR | HMPREF0758_2477 | HMPREF0758_0858 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | 0.731 |
| hmpA | ric | HMPREF0758_2477 | HMPREF0758_0843 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.972 |
| hmpA | rubA | HMPREF0758_2477 | HMPREF0758_0910 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Rubredoxin; COG: COG1773; Pfam: PF00301; InterPro: IPR004039; Belongs to the rubredoxin family. | 0.784 |
| nsrR | hcr | HMPREF0758_0858 | HMPREF0758_4466 | HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.436 |
| nsrR | hmpA | HMPREF0758_0858 | HMPREF0758_2477 | HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.731 |
| nsrR | ric | HMPREF0758_0858 | HMPREF0758_0843 | HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. | 0.430 |
| nsrR | rubA | HMPREF0758_0858 | HMPREF0758_0910 | HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. | Rubredoxin; COG: COG1773; Pfam: PF00301; InterPro: IPR004039; Belongs to the rubredoxin family. | 0.487 |