| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ansA2 | aspA | HMPREF0758_4389 | HMPREF0758_0894 | L-asparaginase, type II; COG: COG0252; Pfam: PF00710; InterPro: IPR004550; Belongs to the asparaginase 1 family. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.955 |
| ansA2 | dcuA | HMPREF0758_4389 | HMPREF0758_0895 | L-asparaginase, type II; COG: COG0252; Pfam: PF00710; InterPro: IPR004550; Belongs to the asparaginase 1 family. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.453 |
| aspA | ansA2 | HMPREF0758_0894 | HMPREF0758_4389 | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | L-asparaginase, type II; COG: COG0252; Pfam: PF00710; InterPro: IPR004550; Belongs to the asparaginase 1 family. | 0.955 |
| aspA | dcuA | HMPREF0758_0894 | HMPREF0758_0895 | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.765 |
| aspA | fumB | HMPREF0758_0894 | HMPREF0758_2124 | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.502 |
| cutA | dcuA | HMPREF0758_0896 | HMPREF0758_0895 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.493 |
| cutA | dsbD | HMPREF0758_0896 | HMPREF0758_0897 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.870 |
| cutA | yjdC | HMPREF0758_0896 | HMPREF0758_0898 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.753 |
| dcuA | ansA2 | HMPREF0758_0895 | HMPREF0758_4389 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | L-asparaginase, type II; COG: COG0252; Pfam: PF00710; InterPro: IPR004550; Belongs to the asparaginase 1 family. | 0.453 |
| dcuA | aspA | HMPREF0758_0895 | HMPREF0758_0894 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Aspartate ammonia-lyase; COG: COG1027; Pfam: PF00206; InterPro: IPR004708. | 0.765 |
| dcuA | cutA | HMPREF0758_0895 | HMPREF0758_0896 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.493 |
| dcuA | dcuC | HMPREF0758_0895 | HMPREF0758_4574 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | 0.520 |
| dcuA | dmsA | HMPREF0758_0895 | HMPREF0758_4445 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; COG: COG0243; Pfam: PF04879,PF00384,PF01568; InterPro: IPR011888; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.442 |
| dcuA | dmsD | HMPREF0758_0895 | HMPREF0758_4442 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Cytoplasmic chaperone TorD; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein. | 0.529 |
| dcuA | dsbD | HMPREF0758_0895 | HMPREF0758_0897 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.516 |
| dcuA | fumB | HMPREF0758_0895 | HMPREF0758_2124 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.527 |
| dcuA | manX | HMPREF0758_0895 | HMPREF0758_3325 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720. | 0.420 |
| dcuA | yjdC | HMPREF0758_0895 | HMPREF0758_0898 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.477 |
| dcuC | dcuA | HMPREF0758_4574 | HMPREF0758_0895 | Transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family; COG: COG3069; Pfam: PF03606; InterPro: IPR004669. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.520 |
| dmsA | dcuA | HMPREF0758_4445 | HMPREF0758_0895 | Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; COG: COG0243; Pfam: PF04879,PF00384,PF01568; InterPro: IPR011888; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.442 |