| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| actP | cutA | HMPREF0758_0141 | HMPREF0758_0896 | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.418 |
| cutA | actP | HMPREF0758_0896 | HMPREF0758_0141 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Copper-exporting ATPase; COG: COG2217; Pfam: PF00403,PF00122,PF00702; InterPro: IPR001757. | 0.418 |
| cutA | dcuA | HMPREF0758_0896 | HMPREF0758_0895 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.493 |
| cutA | dsbD | HMPREF0758_0896 | HMPREF0758_0897 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.870 |
| cutA | fxsA | HMPREF0758_0896 | HMPREF0758_0892 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | FxsA cytoplasmic membrane protein; COG: COG3030; Pfam: PF04186; InterPro: IPR007313. | 0.424 |
| cutA | groS | HMPREF0758_0896 | HMPREF0758_0891 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.404 |
| cutA | scsB | HMPREF0758_0896 | HMPREF0758_2741 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Cytochrome C biogenesis protein transmembrane region; Pfam: PF02683; InterPro: IPR012335. | 0.474 |
| cutA | yjdC | HMPREF0758_0896 | HMPREF0758_0898 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.753 |
| dcuA | cutA | HMPREF0758_0895 | HMPREF0758_0896 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.493 |
| dcuA | dsbD | HMPREF0758_0895 | HMPREF0758_0897 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.516 |
| dcuA | yjdC | HMPREF0758_0895 | HMPREF0758_0898 | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.477 |
| dsbD | cutA | HMPREF0758_0897 | HMPREF0758_0896 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.870 |
| dsbD | dcuA | HMPREF0758_0897 | HMPREF0758_0895 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Transporter, anaerobic C4-dicarboxylate uptake (Dcu) family; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. | 0.516 |
| dsbD | groS | HMPREF0758_0897 | HMPREF0758_0891 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.433 |
| dsbD | yjdC | HMPREF0758_0897 | HMPREF0758_0898 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.702 |
| fxsA | cutA | HMPREF0758_0892 | HMPREF0758_0896 | FxsA cytoplasmic membrane protein; COG: COG3030; Pfam: PF04186; InterPro: IPR007313. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.424 |
| fxsA | groS | HMPREF0758_0892 | HMPREF0758_0891 | FxsA cytoplasmic membrane protein; COG: COG3030; Pfam: PF04186; InterPro: IPR007313. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.657 |
| groS | cutA | HMPREF0758_0891 | HMPREF0758_0896 | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.404 |
| groS | dsbD | HMPREF0758_0891 | HMPREF0758_0897 | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.433 |
| groS | fxsA | HMPREF0758_0891 | HMPREF0758_0892 | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | FxsA cytoplasmic membrane protein; COG: COG3030; Pfam: PF04186; InterPro: IPR007313. | 0.657 |