| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| com | dsbD | HMPREF0758_5043 | HMPREF0758_0897 | DsbA-like protein; COG: COG1651; Pfam: PF01323; InterPro: IPR001853. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.714 |
| com | traF | HMPREF0758_5043 | HMPREF0758_5036 | DsbA-like protein; COG: COG1651; Pfam: PF01323; InterPro: IPR001853. | type-F conjugative transfer system pilin assembly protein TraF; InterPro: IPR014110. | 0.785 |
| cutA | dsbD | HMPREF0758_0896 | HMPREF0758_0897 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.870 |
| cutA | yjdC | HMPREF0758_0896 | HMPREF0758_0898 | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.753 |
| dsbC | dsbD | HMPREF0758_2236 | HMPREF0758_0897 | Putative Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.905 |
| dsbC | dsbE | HMPREF0758_2236 | HMPREF0758_2715 | Putative Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Thiol:disulfide interchange protein DsbE; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | 0.468 |
| dsbD | com | HMPREF0758_0897 | HMPREF0758_5043 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | DsbA-like protein; COG: COG1651; Pfam: PF01323; InterPro: IPR001853. | 0.714 |
| dsbD | cutA | HMPREF0758_0897 | HMPREF0758_0896 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Divalent cation tolerance protein, CutA1 family; Involved in resistance toward heavy metals. Belongs to the CutA family. | 0.870 |
| dsbD | dsbC | HMPREF0758_0897 | HMPREF0758_2236 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Putative Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.905 |
| dsbD | dsbE | HMPREF0758_0897 | HMPREF0758_2715 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Thiol:disulfide interchange protein DsbE; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | 0.891 |
| dsbD | msrA | HMPREF0758_0897 | HMPREF0758_0836 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.679 |
| dsbD | msrB | HMPREF0758_0897 | HMPREF0758_3494 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | methionine-R-sulfoxide reductase; COG: COG0229; Pfam: PF01641; InterPro: IPR002579; Belongs to the MsrB Met sulfoxide reductase family. | 0.681 |
| dsbD | scsC | HMPREF0758_0897 | HMPREF0758_2742 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | DsbA-like protein; Pfam: PF01323; InterPro: IPR012335. | 0.714 |
| dsbD | scsD | HMPREF0758_0897 | HMPREF0758_2743 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Antioxidant, AhpC/TSA family; COG: COG0526; Pfam: PF00578; InterPro: IPR012335. | 0.706 |
| dsbD | traF | HMPREF0758_0897 | HMPREF0758_5036 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | type-F conjugative transfer system pilin assembly protein TraF; InterPro: IPR014110. | 0.679 |
| dsbD | yjdC | HMPREF0758_0897 | HMPREF0758_0898 | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | Transcriptional regulator, TetR family; Pfam: PF00440. | 0.702 |
| dsbE | dsbC | HMPREF0758_2715 | HMPREF0758_2236 | Thiol:disulfide interchange protein DsbE; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | Putative Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.468 |
| dsbE | dsbD | HMPREF0758_2715 | HMPREF0758_0897 | Thiol:disulfide interchange protein DsbE; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | Thioredoxin; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.891 |
| dsbE | msrA | HMPREF0758_2715 | HMPREF0758_0836 | Thiol:disulfide interchange protein DsbE; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.781 |
| dsbE | msrB | HMPREF0758_2715 | HMPREF0758_3494 | Thiol:disulfide interchange protein DsbE; COG: COG0526; Pfam: PF08534; InterPro: IPR004799. | methionine-R-sulfoxide reductase; COG: COG0229; Pfam: PF01641; InterPro: IPR002579; Belongs to the MsrB Met sulfoxide reductase family. | 0.474 |