| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bfd | EFE95061.1 | HMPREF0758_0964 | HMPREF0758_3495 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | 0.405 |
| Bfd | TonB | HMPREF0758_0964 | HMPREF0758_3534 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.417 |
| Bfd | bfr | HMPREF0758_0964 | HMPREF0758_0963 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.919 |
| Bfd | hpaC | HMPREF0758_0964 | HMPREF0758_0648 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; COG: COG1853; Pfam: PF01613; InterPro: IPR002563. | 0.423 |
| Bfd | nirB-2 | HMPREF0758_0964 | HMPREF0758_3251 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | Nitrite reductase [NAD(P)H], large subunit; COG: COG1251; Pfam: PF07992,PF00070,PF04324,PF03460,PF01077; InterPro: IPR012744; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.512 |
| Bfd | tonB | HMPREF0758_0964 | HMPREF0758_0666 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | TonB family domain protein. | 0.417 |
| Bfd | xylR | HMPREF0758_0964 | HMPREF0758_1439 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.407 |
| Bfd | ygiN | HMPREF0758_0964 | HMPREF0758_1961 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | Antibiotic biosynthesis monooxygenase; COG: COG1359; Pfam: PF03992. | 0.538 |
| Bfd | yhgI | HMPREF0758_0964 | HMPREF0758_1052 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.423 |
| Bfd | yiiD | HMPREF0758_0964 | HMPREF0758_1292 | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | 0.414 |
| EFE95061.1 | Bfd | HMPREF0758_3495 | HMPREF0758_0964 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.405 |
| EFE95061.1 | yhgI | HMPREF0758_3495 | HMPREF0758_1052 | Hypothetical protein; COG: COG3139; Pfam: PF07023; InterPro: IPR009749. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.690 |
| TonB | Bfd | HMPREF0758_3534 | HMPREF0758_0964 | TonB-dependent receptor; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.417 |
| bfr | Bfd | HMPREF0758_0963 | HMPREF0758_0964 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.919 |
| bfr | yhgI | HMPREF0758_0963 | HMPREF0758_1052 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.405 |
| hpaC | Bfd | HMPREF0758_0648 | HMPREF0758_0964 | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; COG: COG1853; Pfam: PF01613; InterPro: IPR002563. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.423 |
| nirB-2 | Bfd | HMPREF0758_3251 | HMPREF0758_0964 | Nitrite reductase [NAD(P)H], large subunit; COG: COG1251; Pfam: PF07992,PF00070,PF04324,PF03460,PF01077; InterPro: IPR012744; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.512 |
| nirB-2 | yhgI | HMPREF0758_3251 | HMPREF0758_1052 | Nitrite reductase [NAD(P)H], large subunit; COG: COG1251; Pfam: PF07992,PF00070,PF04324,PF03460,PF01077; InterPro: IPR012744; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.607 |
| tonB | Bfd | HMPREF0758_0666 | HMPREF0758_0964 | TonB family domain protein. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.417 |
| xylR | Bfd | HMPREF0758_1439 | HMPREF0758_0964 | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | [2Fe-2S]-binding domain protein; COG: COG2906; Pfam: PF04324; InterPro: IPR007419. | 0.407 |