| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AcxA | codA | HMPREF0758_3783 | HMPREF0758_1011 | Hydantoinase/oxoprolinase; COG: COG0145; Pfam: PF05378,PF01968; InterPro: IPR002821. | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | 0.900 |
| AcxA | hyuB | HMPREF0758_3783 | HMPREF0758_3784 | Hydantoinase/oxoprolinase; COG: COG0145; Pfam: PF05378,PF01968; InterPro: IPR002821. | Hydantoinase B/oxoprolinase; COG: COG0146; Pfam: PF02538; InterPro: IPR003692. | 0.999 |
| EFE97319.1 | codA | HMPREF0758_1013 | HMPREF0758_1011 | Hypothetical protein. | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | 0.568 |
| EFE97319.1 | codB | HMPREF0758_1013 | HMPREF0758_1012 | Hypothetical protein. | Cytosine permease; COG: COG1457; Pfam: PF02133; InterPro: IPR001248. | 0.568 |
| codA | AcxA | HMPREF0758_1011 | HMPREF0758_3783 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Hydantoinase/oxoprolinase; COG: COG0145; Pfam: PF05378,PF01968; InterPro: IPR002821. | 0.900 |
| codA | EFE97319.1 | HMPREF0758_1011 | HMPREF0758_1013 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Hypothetical protein. | 0.568 |
| codA | codB | HMPREF0758_1011 | HMPREF0758_1012 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Cytosine permease; COG: COG1457; Pfam: PF02133; InterPro: IPR001248. | 0.967 |
| codA | deoA | HMPREF0758_1011 | HMPREF0758_0614 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.915 |
| codA | deoD | HMPREF0758_1011 | HMPREF0758_0612 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.900 |
| codA | hyuB | HMPREF0758_1011 | HMPREF0758_3784 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Hydantoinase B/oxoprolinase; COG: COG0146; Pfam: PF02538; InterPro: IPR003692. | 0.900 |
| codA | ppnP | HMPREF0758_1011 | HMPREF0758_0252 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
| codA | udp | HMPREF0758_1011 | HMPREF0758_1630 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.904 |
| codA | upp | HMPREF0758_1011 | HMPREF0758_2592 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.931 |
| codA | ygdH | HMPREF0758_1011 | HMPREF0758_2318 | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | Putative lysine decarboxylase; COG: COG1611; Pfam: PF03641; InterPro: IPR005269. | 0.902 |
| codB | EFE97319.1 | HMPREF0758_1012 | HMPREF0758_1013 | Cytosine permease; COG: COG1457; Pfam: PF02133; InterPro: IPR001248. | Hypothetical protein. | 0.568 |
| codB | codA | HMPREF0758_1012 | HMPREF0758_1011 | Cytosine permease; COG: COG1457; Pfam: PF02133; InterPro: IPR001248. | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | 0.967 |
| codB | upp | HMPREF0758_1012 | HMPREF0758_2592 | Cytosine permease; COG: COG1457; Pfam: PF02133; InterPro: IPR001248. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.460 |
| deoA | codA | HMPREF0758_0614 | HMPREF0758_1011 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Amidohydrolase family protein; COG: COG0402; Pfam: PF07969; InterPro: IPR013108. | 0.915 |
| deoA | deoD | HMPREF0758_0614 | HMPREF0758_0612 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.978 |
| deoA | ppnP | HMPREF0758_0614 | HMPREF0758_0252 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.913 |