STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpGPeptidase, S54 family; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. (295 aa)    
Predicted Functional Partners:
glpE
Rhodanese-like protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
 
  
 0.722
tatA
Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily.
   
 
 0.693
glpR2
Transcriptional regulator, DeoR family; COG: COG1349; Pfam: PF08220,PF00455; InterPro: IPR014036.
     
 0.684
tatB
Twin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
   
 
 0.673
hflC
SPFH/Band 7/PHB domain protein; COG: COG0330; Pfam: PF01145; InterPro: IPR001107.
   
 0.639
hflC-2
HflC protein; HflC and HflK could regulate a protease.
   
 0.632
hflK
HflK protein; HflC and HflK could encode or regulate a protease.
   
 0.632
amiB
N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508.
  
 
 0.601
YgfA
5-formyltetrahydrofolate cyclo-ligase; COG: COG0212; Pfam: PF01812; InterPro: IPR002698; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.589
mclA
Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...]
  
   
 0.587
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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