STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolE2AP endonuclease, family 2; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family. (304 aa)    
Predicted Functional Partners:
iolD
Thiamine pyrophosphate enzyme, central domain protein; COG: COG3962; Pfam: PF02776,PF00205,PF02775; InterPro: IPR011766; Belongs to the TPP enzyme family.
 
 
 0.994
iolG
Oxidoreductase, NAD-binding domain protein; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
 
 0.993
EFE97253.1
AP endonuclease, family 2; COG: COG4130; Pfam: PF01261; InterPro: IPR013022.
 
 
  0.990
IolG_2
Oxidoreductase, NAD-binding domain protein; COG: COG0673; Pfam: PF01408,PF02894; InterPro: IPR016040.
 
 
 0.984
iolH
AP endonuclease, family 2; COG: COG1082; Pfam: PF01261; InterPro: IPR013022.
 
  
 0.949
iolC
Kinase, PfkB family; COG: COG0524; Pfam: PF00294; InterPro: IPR011611.
  
 0.937
Afr_2
Oxidoreductase, NAD-binding domain protein; COG: COG0673; Pfam: PF01408,PF02894; InterPro: IPR016040.
  
 0.935
iolB
Myo-inositol catabolism protein IolB; COG: COG3718; Pfam: PF06845; InterPro: IPR010669.
 
  
 0.916
rpiR
SIS domain protein; COG: COG1737; Pfam: PF01418,PF01380; InterPro: IPR001347.
 
     0.726
mmsA
Methylmalonate-semialdehyde dehydrogenase (acylating); COG: COG1012; Pfam: PF00171; InterPro: IPR010061.
 
  
 0.598
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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