| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE97270.1 | cpdC | HMPREF0758_1098 | HMPREF0758_1097 | Hypothetical protein; InterPro: IPR006179; overlaps another CDS with the same product name; 3.1.4.16. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; overlaps another CDS with the same product name; Belongs to the 5'-nucleotidase family. | 0.981 |
| EFE97270.1 | ushA | HMPREF0758_1098 | HMPREF0758_0145 | Hypothetical protein; InterPro: IPR006179; overlaps another CDS with the same product name; 3.1.4.16. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.447 |
| add | cdd | HMPREF0758_3853 | HMPREF0758_4586 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.498 |
| add | cpdB | HMPREF0758_3853 | HMPREF0758_0842 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.911 |
| add | cpdC | HMPREF0758_3853 | HMPREF0758_1097 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; overlaps another CDS with the same product name; Belongs to the 5'-nucleotidase family. | 0.911 |
| add | deoD | HMPREF0758_3853 | HMPREF0758_0612 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.914 |
| add | rihA | HMPREF0758_3853 | HMPREF0758_1823 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | Inosine-uridine preferring nucleoside hydrolase; COG: COG1957; Pfam: PF01156; InterPro: IPR001910; Belongs to the IUNH family. | 0.915 |
| add | surE | HMPREF0758_3853 | HMPREF0758_0436 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.913 |
| add | ushA | HMPREF0758_3853 | HMPREF0758_0145 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.924 |
| add | yrfG | HMPREF0758_3853 | HMPREF0758_1034 | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | 0.912 |
| cdd | add | HMPREF0758_4586 | HMPREF0758_3853 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 0.498 |
| cdd | cpdB | HMPREF0758_4586 | HMPREF0758_0842 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.904 |
| cdd | cpdC | HMPREF0758_4586 | HMPREF0758_1097 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; overlaps another CDS with the same product name; Belongs to the 5'-nucleotidase family. | 0.904 |
| cdd | deoD | HMPREF0758_4586 | HMPREF0758_0612 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Purine nucleoside phosphorylase; COG: COG0813; Pfam: PF01048; InterPro: IPR000845. | 0.929 |
| cdd | surE | HMPREF0758_4586 | HMPREF0758_0436 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 5'/3'-nucleotidase SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.913 |
| cdd | udk | HMPREF0758_4586 | HMPREF0758_4577 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.926 |
| cdd | ushA | HMPREF0758_4586 | HMPREF0758_0145 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 5'-nucleotidase, C-terminal domain protein; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | 0.906 |
| cdd | yrfG | HMPREF0758_4586 | HMPREF0758_1034 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | 0.900 |
| cpdB | add | HMPREF0758_0842 | HMPREF0758_3853 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Adenosine deaminase; COG: COG1816; Pfam: PF00962; InterPro: IPR006330. | 0.911 |
| cpdB | cdd | HMPREF0758_0842 | HMPREF0758_4586 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG: COG0737; Pfam: PF00149,PF02872; InterPro: IPR006179; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.904 |