| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atpF | grxC | HMPREF0758_1330 | HMPREF0758_1238 | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.648 |
| atpF | ppa | HMPREF0758_1330 | HMPREF0758_0832 | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.958 |
| atpF | pspE | HMPREF0758_1330 | HMPREF0758_1239 | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. | Rhodanese-like protein; COG: COG0607; Pfam: PF00581; InterPro: IPR001763. | 0.518 |
| gpsA | grxC | HMPREF0758_1236 | HMPREF0758_1238 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.607 |
| gpsA | pspE | HMPREF0758_1236 | HMPREF0758_1239 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Rhodanese-like protein; COG: COG0607; Pfam: PF00581; InterPro: IPR001763. | 0.483 |
| gpsA | secB | HMPREF0758_1236 | HMPREF0758_1237 | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.891 |
| grxC | atpF | HMPREF0758_1238 | HMPREF0758_1330 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. | 0.648 |
| grxC | gpsA | HMPREF0758_1238 | HMPREF0758_1236 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Putative glycerol-3-phosphate dehydrogenase [NAD(P)+]; COG: COG0240; Pfam: PF01210,PF07479; InterPro: IPR006168; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.607 |
| grxC | grxD | HMPREF0758_1238 | HMPREF0758_3922 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Monothiol glutaredoxin, Grx4 family; COG: COG0278; Pfam: PF00462; InterPro: IPR012335; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.741 |
| grxC | nrdA | HMPREF0758_1238 | HMPREF0758_2829 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.634 |
| grxC | nrdE | HMPREF0758_1238 | HMPREF0758_2398 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.634 |
| grxC | nrdI | HMPREF0758_1238 | HMPREF0758_2399 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.583 |
| grxC | ppa | HMPREF0758_1238 | HMPREF0758_0832 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.543 |
| grxC | pspE | HMPREF0758_1238 | HMPREF0758_1239 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Rhodanese-like protein; COG: COG0607; Pfam: PF00581; InterPro: IPR001763. | 0.959 |
| grxC | rpoZ | HMPREF0758_1238 | HMPREF0758_1279 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.526 |
| grxC | secB | HMPREF0758_1238 | HMPREF0758_1237 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.954 |
| grxD | grxC | HMPREF0758_3922 | HMPREF0758_1238 | Monothiol glutaredoxin, Grx4 family; COG: COG0278; Pfam: PF00462; InterPro: IPR012335; Belongs to the glutaredoxin family. Monothiol subfamily. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.741 |
| grxD | rpoZ | HMPREF0758_3922 | HMPREF0758_1279 | Monothiol glutaredoxin, Grx4 family; COG: COG0278; Pfam: PF00462; InterPro: IPR012335; Belongs to the glutaredoxin family. Monothiol subfamily. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.482 |
| nrdA | grxC | HMPREF0758_2829 | HMPREF0758_1238 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.634 |
| nrdA | nrdE | HMPREF0758_2829 | HMPREF0758_2398 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.900 |