| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE97168.1 | coaD | HMPREF0758_1260 | HMPREF0758_1261 | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.830 |
| EFE97168.1 | kdtA | HMPREF0758_1260 | HMPREF0758_1259 | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.850 |
| acpH | coaA | HMPREF0758_0235 | HMPREF0758_1653 | Hypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | 0.910 |
| acpH | coaBC | HMPREF0758_0235 | HMPREF0758_1266 | Hypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | 0.900 |
| acpH | coaD | HMPREF0758_0235 | HMPREF0758_1261 | Hypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.904 |
| coaA | acpH | HMPREF0758_1653 | HMPREF0758_0235 | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | Hypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. | 0.910 |
| coaA | coaBC | HMPREF0758_1653 | HMPREF0758_1266 | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | 0.918 |
| coaA | coaD | HMPREF0758_1653 | HMPREF0758_1261 | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.934 |
| coaA | coaE | HMPREF0758_1653 | HMPREF0758_0500 | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.506 |
| coaBC | acpH | HMPREF0758_1266 | HMPREF0758_0235 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | Hypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. | 0.900 |
| coaBC | coaA | HMPREF0758_1266 | HMPREF0758_1653 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | 0.918 |
| coaBC | coaD | HMPREF0758_1266 | HMPREF0758_1261 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.935 |
| coaBC | coaE | HMPREF0758_1266 | HMPREF0758_0500 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.500 |
| coaBC | guaA-2 | HMPREF0758_1266 | HMPREF0758_2515 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.412 |
| coaBC | ribF | HMPREF0758_1266 | HMPREF0758_0575 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family. | 0.557 |
| coaD | EFE97168.1 | HMPREF0758_1261 | HMPREF0758_1260 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Glycosyltransferase, group 2 family protein; COG: COG0463; Pfam: PF00535; InterPro: IPR001173. | 0.830 |
| coaD | acpH | HMPREF0758_1261 | HMPREF0758_0235 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Hypothetical protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. | 0.904 |
| coaD | coaA | HMPREF0758_1261 | HMPREF0758_1653 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate kinase; COG: COG1072; Pfam: PF00485; InterPro: IPR004566. | 0.934 |
| coaD | coaBC | HMPREF0758_1261 | HMPREF0758_1266 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG: COG0452; Pfam: PF02441,PF04127; InterPro: IPR005252. | 0.935 |
| coaD | coaE | HMPREF0758_1261 | HMPREF0758_0500 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.949 |