| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| coaD | gmk | HMPREF0758_1261 | HMPREF0758_1278 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.559 |
| coaD | kdpF | HMPREF0758_1261 | HMPREF0758_1272 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | 0.572 |
| gltB | kdpF | HMPREF0758_1877 | HMPREF0758_1272 | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | 0.706 |
| gmk | coaD | HMPREF0758_1278 | HMPREF0758_1261 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.559 |
| gmk | kdpF | HMPREF0758_1278 | HMPREF0758_1272 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | 0.595 |
| gmk | pyrE | HMPREF0758_1278 | HMPREF0758_1270 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.470 |
| gmk | rpoZ | HMPREF0758_1278 | HMPREF0758_1279 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.981 |
| kdpF | coaD | HMPREF0758_1272 | HMPREF0758_1261 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.572 |
| kdpF | gltB | HMPREF0758_1272 | HMPREF0758_1877 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.706 |
| kdpF | gmk | HMPREF0758_1272 | HMPREF0758_1278 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.595 |
| kdpF | pyrE | HMPREF0758_1272 | HMPREF0758_1270 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.461 |
| kdpF | rph | HMPREF0758_1272 | HMPREF0758_1271 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.592 |
| kdpF | rpoZ | HMPREF0758_1272 | HMPREF0758_1279 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.500 |
| kdpF | yeaZ | HMPREF0758_1272 | HMPREF0758_3453 | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | Universal bacterial protein YeaZ; COG: COG1214; Pfam: PF00814; InterPro: IPR000905. | 0.443 |
| pyrE | gmk | HMPREF0758_1270 | HMPREF0758_1278 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.470 |
| pyrE | kdpF | HMPREF0758_1270 | HMPREF0758_1272 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | 0.461 |
| pyrE | rph | HMPREF0758_1270 | HMPREF0758_1271 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.752 |
| rph | kdpF | HMPREF0758_1271 | HMPREF0758_1272 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | TIGR00255 family protein; COG: COG1561; Pfam: PF03755,PF08340; InterPro: IPR005229. | 0.592 |
| rph | pyrE | HMPREF0758_1271 | HMPREF0758_1270 | tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.752 |
| rpoZ | gmk | HMPREF0758_1279 | HMPREF0758_1278 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.981 |