| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| YihX | dtd | HMPREF0758_1295 | HMPREF0758_1293 | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.658 |
| YihX | rbn | HMPREF0758_1295 | HMPREF0758_1294 | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | 0.890 |
| YihX | typA | HMPREF0758_1295 | HMPREF0758_1296 | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.607 |
| YihX | yiiD | HMPREF0758_1295 | HMPREF0758_1292 | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | 0.527 |
| dtd | YihX | HMPREF0758_1293 | HMPREF0758_1295 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | 0.658 |
| dtd | metG | HMPREF0758_1293 | HMPREF0758_4580 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.427 |
| dtd | rbn | HMPREF0758_1293 | HMPREF0758_1294 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | 0.805 |
| dtd | typA | HMPREF0758_1293 | HMPREF0758_1296 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.542 |
| dtd | yiiD | HMPREF0758_1293 | HMPREF0758_1292 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | 0.680 |
| metG | dtd | HMPREF0758_4580 | HMPREF0758_1293 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.427 |
| rbn | YihX | HMPREF0758_1294 | HMPREF0758_1295 | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | 0.890 |
| rbn | dtd | HMPREF0758_1294 | HMPREF0758_1293 | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.805 |
| rbn | typA | HMPREF0758_1294 | HMPREF0758_1296 | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.544 |
| rbn | yiiD | HMPREF0758_1294 | HMPREF0758_1292 | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | 0.536 |
| typA | YihX | HMPREF0758_1296 | HMPREF0758_1295 | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | 0.607 |
| typA | dtd | HMPREF0758_1296 | HMPREF0758_1293 | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.542 |
| typA | rbn | HMPREF0758_1296 | HMPREF0758_1294 | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | 0.544 |
| yiiD | YihX | HMPREF0758_1292 | HMPREF0758_1295 | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | 0.527 |
| yiiD | dtd | HMPREF0758_1292 | HMPREF0758_1293 | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.680 |
| yiiD | rbn | HMPREF0758_1292 | HMPREF0758_1294 | Putative thioesterase domain protein; Pfam: PF00583; InterPro: IPR016181. | tRNA-processing ribonuclease BN; COG: COG1295; Pfam: PF03631; InterPro: IPR004664. | 0.536 |