| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94253.1 | rplA | HMPREF0758_4348 | HMPREF0758_1659 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.621 |
| EFE94253.1 | rpsJ | HMPREF0758_4348 | HMPREF0758_0962 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.621 |
| EFE94253.1 | typA | HMPREF0758_4348 | HMPREF0758_1296 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.643 |
| YihX | typA | HMPREF0758_1295 | HMPREF0758_1296 | HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.607 |
| der | guaA-2 | HMPREF0758_2505 | HMPREF0758_2515 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.515 |
| der | rplA | HMPREF0758_2505 | HMPREF0758_1659 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.653 |
| der | typA | HMPREF0758_2505 | HMPREF0758_1296 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.800 |
| der | ychF | HMPREF0758_2505 | HMPREF0758_3383 | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.484 |
| guaA-2 | der | HMPREF0758_2515 | HMPREF0758_2505 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.515 |
| guaA-2 | rplA | HMPREF0758_2515 | HMPREF0758_1659 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.963 |
| guaA-2 | rpoB | HMPREF0758_2515 | HMPREF0758_1662 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.881 |
| guaA-2 | rpsA | HMPREF0758_2515 | HMPREF0758_4383 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.673 |
| guaA-2 | rpsJ | HMPREF0758_2515 | HMPREF0758_0962 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.616 |
| guaA-2 | tig | HMPREF0758_2515 | HMPREF0758_0202 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.550 |
| guaA-2 | typA | HMPREF0758_2515 | HMPREF0758_1296 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein TypA; COG: COG1217; Pfam: PF00009,PF03144,PF00679; InterPro: IPR006298. | 0.757 |
| guaA-2 | ychF | HMPREF0758_2515 | HMPREF0758_3383 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.703 |
| rplA | EFE94253.1 | HMPREF0758_1659 | HMPREF0758_4348 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | 0.621 |
| rplA | der | HMPREF0758_1659 | HMPREF0758_2505 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.653 |
| rplA | guaA-2 | HMPREF0758_1659 | HMPREF0758_2515 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.963 |
| rplA | rpoB | HMPREF0758_1659 | HMPREF0758_1662 | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.982 |