STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxB4-phosphoerythronate dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (325 aa)    
Predicted Functional Partners:
glxR
2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.
 
  
 0.924
pdxB-3
4-phosphoerythronate dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
 
  
0.920
gph
Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
 0.919
aceB
Malate synthase A; COG: COG2225; Pfam: PF01274; InterPro: IPR001465; Belongs to the malate synthase family.
  
 
 0.919
hyi
AP endonuclease, family 2; COG: COG3622; Pfam: PF01261; InterPro: IPR013022; Belongs to the hyi family.
  
 
 0.918
pdxB-5
4-phosphoerythronate dehydrogenase; COG: COG0111; Pfam: PF02826; InterPro: IPR016040.
 
  
0.916
EFE94419.1
Tat pathway signal sequence domain protein.
  
 
 0.912
aceA
Isocitrate lyase; COG: COG2224; Pfam: PF00463; InterPro: IPR015813.
     
 0.911
glxK
Glycerate kinase; COG: COG1929; Pfam: PF02595; InterPro: IPR004381; Belongs to the glycerate kinase type-1 family.
    
 0.910
glxK2
Glycerate kinase; COG: COG1929; Pfam: PF02595; InterPro: IPR004381; Belongs to the glycerate kinase type-1 family.
    
 0.910
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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