STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DegA_2Hypothetical protein; COG: COG1609. (192 aa)    
Predicted Functional Partners:
CytR_3
Hypothetical protein; COG: COG1609.
  
     0.764
malI
Sugar-binding domain protein; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR001761.
  
     0.764
purR
Sugar-binding domain protein; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR001761.
  
     0.759
GalR_4
Transcriptional regulator, LacI family; COG: COG1609; Pfam: PF00356; InterPro: IPR000843.
  
     0.758
AscG_2
Transcriptional regulator, LacI family; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR000843.
  
     0.757
lacI
Lac repressor; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR000843.
  
     0.751
cytR
Transcriptional regulator, LacI family; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR001761.
  
     0.749
lacI-2
Lac repressor; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR000843.
  
     0.749
scrR
D-fructose-responsive transcription factor; COG: COG1609; Pfam: PF00356,PF00532; InterPro: IPR012781.
  
     0.748
rbsR2
Sugar-binding domain protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
  
     0.748
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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