| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96815.1 | sodA | HMPREF0758_1409 | HMPREF0758_1411 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08241; InterPro: IPR013216. | Superoxide dismutase, Mn/Fe family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.452 |
| EFE96815.1 | yiiM | HMPREF0758_1409 | HMPREF0758_1410 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08241; InterPro: IPR013216. | MOSC domain protein; COG: COG2258; Pfam: PF03473,PF03475; InterPro: IPR015808. | 0.773 |
| fdhD | moaA | HMPREF0758_1412 | HMPREF0758_4790 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.761 |
| fdhD | moaC | HMPREF0758_1412 | HMPREF0758_4788 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.650 |
| fdhD | moaE | HMPREF0758_1412 | HMPREF0758_4786 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Molybdopterin converting factor, subunit 2; COG: COG0314; Pfam: PF02391; InterPro: IPR003448. | 0.587 |
| fdhD | modE | HMPREF0758_1412 | HMPREF0758_4811 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | TOBE domain protein; COG: COG2005; Pfam: PF00126,PF03459; InterPro: IPR005116. | 0.635 |
| fdhD | nasA | HMPREF0758_1412 | HMPREF0758_3252 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Molybdopterin oxidoreductase; COG: COG0243; Pfam: PF04879,PF00384,PF01568,PF04324; InterPro: IPR006656; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.464 |
| fdhD | sodA | HMPREF0758_1412 | HMPREF0758_1411 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | Superoxide dismutase, Mn/Fe family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.559 |
| fdhD | yiiM | HMPREF0758_1412 | HMPREF0758_1410 | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | MOSC domain protein; COG: COG2258; Pfam: PF03473,PF03475; InterPro: IPR015808. | 0.562 |
| hcr | hmpA | HMPREF0758_4466 | HMPREF0758_2477 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.455 |
| hcr | nasA | HMPREF0758_4466 | HMPREF0758_3252 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | Molybdopterin oxidoreductase; COG: COG0243; Pfam: PF04879,PF00384,PF01568,PF04324; InterPro: IPR006656; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.494 |
| hcr | yiiM | HMPREF0758_4466 | HMPREF0758_1410 | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | MOSC domain protein; COG: COG2258; Pfam: PF03473,PF03475; InterPro: IPR015808. | 0.427 |
| hmpA | hcr | HMPREF0758_2477 | HMPREF0758_4466 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. | 0.455 |
| hmpA | moaA | HMPREF0758_2477 | HMPREF0758_4790 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.467 |
| hmpA | nasA | HMPREF0758_2477 | HMPREF0758_3252 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | Molybdopterin oxidoreductase; COG: COG0243; Pfam: PF04879,PF00384,PF01568,PF04324; InterPro: IPR006656; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.494 |
| hmpA | yiiM | HMPREF0758_2477 | HMPREF0758_1410 | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | MOSC domain protein; COG: COG2258; Pfam: PF03473,PF03475; InterPro: IPR015808. | 0.758 |
| moaA | fdhD | HMPREF0758_4790 | HMPREF0758_1412 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.761 |
| moaA | hmpA | HMPREF0758_4790 | HMPREF0758_2477 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Globin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. | 0.467 |
| moaA | moaC | HMPREF0758_4790 | HMPREF0758_4788 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
| moaA | moaE | HMPREF0758_4790 | HMPREF0758_4786 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin converting factor, subunit 2; COG: COG0314; Pfam: PF02391; InterPro: IPR003448. | 0.980 |