| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96820.1 | EFE96821.1 | HMPREF0758_1414 | HMPREF0758_1415 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | 0.991 |
| EFE96820.1 | dmsB | HMPREF0758_1414 | HMPREF0758_4444 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Dimethylsulfoxide reductase, chain B; COG: COG0437; Pfam: PF00037; InterPro: IPR014297. | 0.799 |
| EFE96820.1 | fdhE | HMPREF0758_1414 | HMPREF0758_1418 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. | 0.940 |
| EFE96820.1 | fdnG | HMPREF0758_1414 | HMPREF0758_1413 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Tat pathway signal sequence domain protein; COG: COG0243; Pfam: PF04879,PF00384; InterPro: IPR006963. | 0.990 |
| EFE96820.1 | fdnI | HMPREF0758_1414 | HMPREF0758_1417 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Formate dehydrogenase, gamma subunit; COG: COG2864; Pfam: PF01292; InterPro: IPR006471. | 0.960 |
| EFE96820.1 | fdxH | HMPREF0758_1414 | HMPREF0758_1416 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. | 0.964 |
| EFE96820.1 | napB | HMPREF0758_1414 | HMPREF0758_2624 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Periplasmic nitrate reductase, diheme cytochrome c subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | 0.785 |
| EFE96820.1 | napD | HMPREF0758_1414 | HMPREF0758_2620 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | NapD protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export. | 0.752 |
| EFE96820.1 | selA | HMPREF0758_1414 | HMPREF0758_1421 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. | 0.836 |
| EFE96820.1 | selB | HMPREF0758_1414 | HMPREF0758_1422 | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Selenocysteine-specific translation elongation factor; COG: COG3276; Pfam: PF00009,PF03144,PF09106,PF09107; InterPro: IPR004535. | 0.844 |
| EFE96821.1 | EFE96820.1 | HMPREF0758_1415 | HMPREF0758_1414 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Formate dehydrogenase, alpha subunit; COG: COG0243; Pfam: PF00384; InterPro: IPR006443; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.991 |
| EFE96821.1 | dmsB | HMPREF0758_1415 | HMPREF0758_4444 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Dimethylsulfoxide reductase, chain B; COG: COG0437; Pfam: PF00037; InterPro: IPR014297. | 0.753 |
| EFE96821.1 | fdhE | HMPREF0758_1415 | HMPREF0758_1418 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. | 0.960 |
| EFE96821.1 | fdnG | HMPREF0758_1415 | HMPREF0758_1413 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Tat pathway signal sequence domain protein; COG: COG0243; Pfam: PF04879,PF00384; InterPro: IPR006963. | 0.988 |
| EFE96821.1 | fdnI | HMPREF0758_1415 | HMPREF0758_1417 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Formate dehydrogenase, gamma subunit; COG: COG2864; Pfam: PF01292; InterPro: IPR006471. | 0.973 |
| EFE96821.1 | fdxH | HMPREF0758_1415 | HMPREF0758_1416 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. | 0.976 |
| EFE96821.1 | napB | HMPREF0758_1415 | HMPREF0758_2624 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Periplasmic nitrate reductase, diheme cytochrome c subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | 0.785 |
| EFE96821.1 | napD | HMPREF0758_1415 | HMPREF0758_2620 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | NapD protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export. | 0.752 |
| EFE96821.1 | selA | HMPREF0758_1415 | HMPREF0758_1421 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. | 0.829 |
| EFE96821.1 | selB | HMPREF0758_1415 | HMPREF0758_1422 | Hypothetical protein; COG: COG0243; InterPro: IPR009010; 1.2.1.2. | Selenocysteine-specific translation elongation factor; COG: COG3276; Pfam: PF00009,PF03144,PF09106,PF09107; InterPro: IPR004535. | 0.847 |