| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gltB | ptsP | HMPREF0758_1877 | HMPREF0758_1627 | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | Phosphoenolpyruvate-protein phosphotransferase; COG: COG1080; Pfam: PF00381,PF05524,PF00391,PF02896,PF00359; InterPro: IPR006318. | 0.443 |
| gltB | rpoA | HMPREF0758_1877 | HMPREF0758_0937 | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.426 |
| gltB | xylR | HMPREF0758_1877 | HMPREF0758_1439 | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.634 |
| metJ | xylR | HMPREF0758_1162 | HMPREF0758_1439 | Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.552 |
| ptsP | gltB | HMPREF0758_1627 | HMPREF0758_1877 | Phosphoenolpyruvate-protein phosphotransferase; COG: COG1080; Pfam: PF00381,PF05524,PF00391,PF02896,PF00359; InterPro: IPR006318. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.443 |
| ptsP | xylB | HMPREF0758_1627 | HMPREF0758_1433 | Phosphoenolpyruvate-protein phosphotransferase; COG: COG1080; Pfam: PF00381,PF05524,PF00391,PF02896,PF00359; InterPro: IPR006318. | Xylulokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR006000. | 0.492 |
| ptsP | xylR | HMPREF0758_1627 | HMPREF0758_1439 | Phosphoenolpyruvate-protein phosphotransferase; COG: COG1080; Pfam: PF00381,PF05524,PF00391,PF02896,PF00359; InterPro: IPR006318. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.696 |
| rpoA | gltB | HMPREF0758_0937 | HMPREF0758_1877 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785. | 0.426 |
| rpoA | xylR | HMPREF0758_0937 | HMPREF0758_1439 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.645 |
| xylA | xylB | HMPREF0758_1434 | HMPREF0758_1433 | Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family. | Xylulokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR006000. | 0.990 |
| xylA | xylF | HMPREF0758_1434 | HMPREF0758_1436 | Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family. | D-xylose ABC transporter, D-xylose-binding protein; COG: COG4213; Pfam: PF00532; InterPro: IPR013456. | 0.782 |
| xylA | xylH | HMPREF0758_1434 | HMPREF0758_1438 | Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family. | Branched-chain amino acid ABC transporter, permease protein; COG: COG4214; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family. | 0.535 |
| xylA | xylR | HMPREF0758_1434 | HMPREF0758_1439 | Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.715 |
| xylA2 | xylB | HMPREF0758_2516 | HMPREF0758_1433 | Putative xylose isomerase; COG: COG2115. | Xylulokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR006000. | 0.770 |
| xylA2 | xylF | HMPREF0758_2516 | HMPREF0758_1436 | Putative xylose isomerase; COG: COG2115. | D-xylose ABC transporter, D-xylose-binding protein; COG: COG4213; Pfam: PF00532; InterPro: IPR013456. | 0.760 |
| xylA2 | xylH | HMPREF0758_2516 | HMPREF0758_1438 | Putative xylose isomerase; COG: COG2115. | Branched-chain amino acid ABC transporter, permease protein; COG: COG4214; Pfam: PF02653; InterPro: IPR001851; Belongs to the binding-protein-dependent transport system permease family. | 0.419 |
| xylA2 | xylR | HMPREF0758_2516 | HMPREF0758_1439 | Putative xylose isomerase; COG: COG2115. | Transcriptional regulator, AraC family; Pfam: PF00165; InterPro: IPR000005. | 0.703 |
| xylB | ptsP | HMPREF0758_1433 | HMPREF0758_1627 | Xylulokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR006000. | Phosphoenolpyruvate-protein phosphotransferase; COG: COG1080; Pfam: PF00381,PF05524,PF00391,PF02896,PF00359; InterPro: IPR006318. | 0.492 |
| xylB | xylA | HMPREF0758_1433 | HMPREF0758_1434 | Xylulokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR006000. | Xylose isomerase; COG: COG2115; Pfam: PF01261; InterPro: IPR013022; Belongs to the xylose isomerase family. | 0.990 |
| xylB | xylA2 | HMPREF0758_1433 | HMPREF0758_2516 | Xylulokinase; COG: COG1070; Pfam: PF00370,PF02782; InterPro: IPR006000. | Putative xylose isomerase; COG: COG2115. | 0.770 |