| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96912.1 | wecD | HMPREF0758_1506 | HMPREF0758_1516 | Hypothetical protein; Overlaps another CDS with the same product name; 3.6.1.-. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.719 |
| EFE96912.1 | wecF | HMPREF0758_1506 | HMPREF0758_1519 | Hypothetical protein; Overlaps another CDS with the same product name; 3.6.1.-. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.774 |
| EFE96912.1 | wzxE | HMPREF0758_1506 | HMPREF0758_1518 | Hypothetical protein; Overlaps another CDS with the same product name; 3.6.1.-. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.655 |
| EFE96912.1 | wzyE | HMPREF0758_1506 | HMPREF0758_1520 | Hypothetical protein; Overlaps another CDS with the same product name; 3.6.1.-. | ECA biosynthesis protein WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.743 |
| EFE96912.1 | wzzE | HMPREF0758_1506 | HMPREF0758_1511 | Hypothetical protein; Overlaps another CDS with the same product name; 3.6.1.-. | Chain length determinant protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.662 |
| rfbA | wecD | HMPREF0758_1515 | HMPREF0758_1516 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.794 |
| rfbA | wecE | HMPREF0758_1515 | HMPREF0758_1517 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | dTDP-4-amino-4,6-dideoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.928 |
| rfbA | wecF | HMPREF0758_1515 | HMPREF0758_1519 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.797 |
| rfbA | wecG | HMPREF0758_1515 | HMPREF0758_1521 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Glycosyltransferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.812 |
| rfbA | wzxE | HMPREF0758_1515 | HMPREF0758_1518 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.931 |
| rfbA | wzyE | HMPREF0758_1515 | HMPREF0758_1520 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | ECA biosynthesis protein WzyE; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.802 |
| rfbA | wzzE | HMPREF0758_1515 | HMPREF0758_1511 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Chain length determinant protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.540 |
| vtaK | wecF | HMPREF0758_1762 | HMPREF0758_1519 | NlpC/P60 family protein; COG: COG1310; Pfam: PF00877; InterPro: IPR000555. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.799 |
| vtaK2 | wecF | HMPREF0758_4397 | HMPREF0758_1519 | NlpC/P60 family protein; COG: COG1310; Pfam: PF00877; InterPro: IPR000555. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.799 |
| wecD | EFE96912.1 | HMPREF0758_1516 | HMPREF0758_1506 | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Hypothetical protein; Overlaps another CDS with the same product name; 3.6.1.-. | 0.719 |
| wecD | rfbA | HMPREF0758_1516 | HMPREF0758_1515 | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.794 |
| wecD | wecE | HMPREF0758_1516 | HMPREF0758_1517 | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | dTDP-4-amino-4,6-dideoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.985 |
| wecD | wecF | HMPREF0758_1516 | HMPREF0758_1519 | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.974 |
| wecD | wecG | HMPREF0758_1516 | HMPREF0758_1521 | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Glycosyltransferase, WecB/TagA/CpsF family; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.817 |
| wecD | wzxE | HMPREF0758_1516 | HMPREF0758_1518 | TDP-D-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | Polysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.948 |