STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yigBHAD hydrolase, family IA, variant 1; COG: COG1011; Pfam: PF00702; InterPro: IPR005834. (238 aa)    
Predicted Functional Partners:
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.945
ribF
Riboflavin biosynthesis protein RibF; COG: COG0196; Pfam: PF06574,PF01687; InterPro: IPR002606; Belongs to the ribF family.
  
 
 0.913
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
     
 0.905
Fre
FMN reductase; COG: COG0543; Pfam: PF00970,PF00175; InterPro: IPR001433.
  
 
 0.904
ribE
Riboflavin synthase, alpha subunit; COG: COG0307; Pfam: PF00677; InterPro: IPR001783.
   
 
 0.904
ssuE
FMN reductase; COG: COG0431; Pfam: PF03358; InterPro: IPR005025.
  
 
  0.902
hpaC
4-hydroxyphenylacetate 3-monooxygenase, reductase component; COG: COG1853; Pfam: PF01613; InterPro: IPR002563.
     
  0.900
phyM
Histidine acid phosphatase; Pfam: PF00328; InterPro: IPR000560.
     
  0.900
nfsA
Nitroreductase family protein; COG: COG0778; Pfam: PF00881; InterPro: IPR000415; Belongs to the flavin oxidoreductase frp family.
     
  0.900
C1-hpah
Flavin reductase-like protein; COG: COG1853; Pfam: PF01613; InterPro: IPR012349.
     
  0.900
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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