| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96951.1 | pldA | HMPREF0758_1545 | HMPREF0758_1546 | Hypothetical protein; COG: COG2050; Pfam: PF03061; InterPro: IPR003736. | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | 0.588 |
| EFE96951.1 | recQ | HMPREF0758_1545 | HMPREF0758_1547 | Hypothetical protein; COG: COG2050; Pfam: PF03061; InterPro: IPR003736. | ATP-dependent DNA helicase RecQ; COG: COG0514; Pfam: PF00270,PF00271,PF00570; InterPro: IPR004589. | 0.476 |
| EFE96951.1 | rhtC | HMPREF0758_1545 | HMPREF0758_1548 | Hypothetical protein; COG: COG2050; Pfam: PF03061; InterPro: IPR003736. | Homoserine/Threonine efflux protein; COG: COG1280; Pfam: PF01810; InterPro: IPR001123. | 0.509 |
| PlcN | aas | HMPREF0758_1988 | HMPREF0758_2288 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | 0.902 |
| PlcN | betA | HMPREF0758_1988 | HMPREF0758_4630 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.800 |
| PlcN | pldA | HMPREF0758_1988 | HMPREF0758_1546 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | 0.901 |
| PlcN | psd | HMPREF0758_1988 | HMPREF0758_0875 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.900 |
| PlcN | pssA | HMPREF0758_1988 | HMPREF0758_2373 | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | Phospholipase D domain protein; COG: COG1502; Pfam: PF00614. | 0.817 |
| aas | PlcN | HMPREF0758_2288 | HMPREF0758_1988 | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | 0.902 |
| aas | betA | HMPREF0758_2288 | HMPREF0758_4630 | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.813 |
| aas | pldA | HMPREF0758_2288 | HMPREF0758_1546 | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | 0.918 |
| aas | pldB | HMPREF0758_2288 | HMPREF0758_1550 | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | Hydrolase, alpha/beta domain protein; COG: COG2267; Pfam: PF00561; InterPro: IPR000073. | 0.927 |
| aas | psd | HMPREF0758_2288 | HMPREF0758_0875 | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.939 |
| aas | pssA | HMPREF0758_2288 | HMPREF0758_2373 | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | Phospholipase D domain protein; COG: COG1502; Pfam: PF00614. | 0.843 |
| betA | PlcN | HMPREF0758_4630 | HMPREF0758_1988 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | 0.800 |
| betA | aas | HMPREF0758_4630 | HMPREF0758_2288 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | AMP-binding enzyme; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. | 0.813 |
| betA | pldA | HMPREF0758_4630 | HMPREF0758_1546 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | 0.822 |
| betA | psd | HMPREF0758_4630 | HMPREF0758_0875 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.800 |
| pldA | EFE96951.1 | HMPREF0758_1546 | HMPREF0758_1545 | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | Hypothetical protein; COG: COG2050; Pfam: PF03061; InterPro: IPR003736. | 0.588 |
| pldA | PlcN | HMPREF0758_1546 | HMPREF0758_1988 | Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. | Phospholipase C, phosphocholine-specific; COG: COG3511; Pfam: PF04185,PF05506; InterPro: IPR007312. | 0.901 |