| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE96776.1 | ubiB | HMPREF0758_1635 | HMPREF0758_1636 | SCP-2 sterol transfer family protein; COG: COG3165; Pfam: PF06843; InterPro: IPR010668. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.811 |
| EFE96776.1 | ubiE | HMPREF0758_1635 | HMPREF0758_1634 | SCP-2 sterol transfer family protein; COG: COG3165; Pfam: PF06843; InterPro: IPR010668. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.887 |
| KefF_2 | ubiE | HMPREF0758_4668 | HMPREF0758_1634 | Flavodoxin-like protein; COG: COG2249; Pfam: PF02525; InterPro: IPR003680. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
| KefF_2 | wrbA | HMPREF0758_4668 | HMPREF0758_4282 | Flavodoxin-like protein; COG: COG2249; Pfam: PF02525; InterPro: IPR003680. | NAD(P)H:quinone oxidoreductase, type IV; COG: COG0655; Pfam: PF00258; InterPro: IPR010089. | 0.919 |
| menA | ubiE | HMPREF0758_1170 | HMPREF0758_1634 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.916 |
| ubiB | EFE96776.1 | HMPREF0758_1636 | HMPREF0758_1635 | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | SCP-2 sterol transfer family protein; COG: COG3165; Pfam: PF06843; InterPro: IPR010668. | 0.811 |
| ubiB | ubiE | HMPREF0758_1636 | HMPREF0758_1634 | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.869 |
| ubiB | ubiF | HMPREF0758_1636 | HMPREF0758_2213 | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG: COG0654; Pfam: PF01266; InterPro: IPR010971. | 0.579 |
| ubiB | ubiF-2 | HMPREF0758_1636 | HMPREF0758_4894 | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; COG: COG0654; Pfam: PF01266; InterPro: IPR010971. | 0.516 |
| ubiB | ubiG | HMPREF0758_1636 | HMPREF0758_2830 | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.572 |
| ubiB | ubiH | HMPREF0758_1636 | HMPREF0758_2212 | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 2-polyprenyl-6-methoxyphenol 4-hydroxylase; COG: COG0654; Pfam: PF01266; InterPro: IPR010971. | 0.430 |
| ubiD | ubiE | HMPREF0758_1642 | HMPREF0758_1634 | UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.639 |
| ubiD | ubiF | HMPREF0758_1642 | HMPREF0758_2213 | UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG: COG0654; Pfam: PF01266; InterPro: IPR010971. | 0.924 |
| ubiE | EFE96776.1 | HMPREF0758_1634 | HMPREF0758_1635 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | SCP-2 sterol transfer family protein; COG: COG3165; Pfam: PF06843; InterPro: IPR010668. | 0.887 |
| ubiE | KefF_2 | HMPREF0758_1634 | HMPREF0758_4668 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | Flavodoxin-like protein; COG: COG2249; Pfam: PF02525; InterPro: IPR003680. | 0.900 |
| ubiE | menA | HMPREF0758_1634 | HMPREF0758_1170 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.916 |
| ubiE | ubiB | HMPREF0758_1634 | HMPREF0758_1636 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.869 |
| ubiE | ubiD | HMPREF0758_1634 | HMPREF0758_1642 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | UbiD family decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.639 |
| ubiE | ubiF | HMPREF0758_1634 | HMPREF0758_2213 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; COG: COG0654; Pfam: PF01266; InterPro: IPR010971. | 0.608 |
| ubiE | ubiF-2 | HMPREF0758_1634 | HMPREF0758_4894 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; COG: COG0654; Pfam: PF01266; InterPro: IPR010971. | 0.943 |