STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiSThiamine biosynthesis protein ThiS; COG: COG2104; Pfam: PF02597; InterPro: IPR012675. (66 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.998
thiF
ThiF family protein; COG: COG0476; Pfam: PF00899,PF05237; InterPro: IPR016040.
 
 
 0.988
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.970
thiH
Thiazole biosynthesis protein ThiH; COG: COG1060; Pfam: PF04055,PF06968; InterPro: IPR012726.
 
  
 0.965
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.961
moeB
Molybdopterin synthase sulfurylase MoeB; COG: COG0476; Pfam: PF00899,PF05237; InterPro: IPR016040.
  
 
 0.837
EFE95236.1
ThiF family protein; Pfam: PF00899; InterPro: IPR016040.
  
 
 0.822
thiD
Phosphomethylpyrimidine kinase; COG: COG0351; Pfam: PF08543; InterPro: IPR004399.
  
    0.810
EFE95237.1
Hypothetical protein; InterPro: IPR011952.
  
 
 0.763
vtaK2
NlpC/P60 family protein; COG: COG1310; Pfam: PF00877; InterPro: IPR000555.
 
 
 0.763
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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