STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
algQRegulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase. (171 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.904
YohC
Hypothetical protein; Pfam: PF06930; InterPro: IPR009698.
  
     0.753
EFE97848.1
Sigma-70, region 4; COG: COG0568; Pfam: PF04539,PF04545; InterPro: IPR011991.
  
 
 0.749
RpoS
Sigma-70 region 2; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.731
ptsH
Phosphocarrier protein HPr; COG: COG1925; Pfam: PF00381; InterPro: IPR000032.
    
 
 0.675
EFE96528.1
Hypothetical protein; COG: COG3151; Pfam: PF06853; InterPro: IPR009659.
  
     0.666
rpoH
Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.656
nudC
NAD(+) diphosphatase; COG: COG2816; Pfam: PF09296,PF09297,PF00293; InterPro: IPR000086; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.586
sirB2
Invasion gene expression up-regulator, SirB; COG: COG3094; Pfam: PF04247; InterPro: IPR007360.
  
     0.493
EFE96836.1
Hypothetical protein; COG: COG3274; overlaps another CDS with the same product name.
  
     0.463
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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