STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrBAminotransferase, class I/II; COG: COG1448; Pfam: PF00155; InterPro: IPR000796. (397 aa)    
Predicted Functional Partners:
pheA
Chorismate mutase; COG: COG0077; Pfam: PF01817,PF00800; InterPro: IPR001086.
    
 0.948
tyrA
Chorismate mutase; COG: COG0287; Pfam: PF01817,PF02153; InterPro: IPR003099.
    
 0.948
pheC
ABC transporter, substrate-binding protein, family 3; COG: COG0834; Pfam: PF00497; InterPro: IPR001638.
    
 0.920
hisC
Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.919
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.917
mtnD
Acireductone dioxygenase (Ni(2+)-requiring); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
     
 0.913
pheA2
Putative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate.
    
 0.912
ldh
malate/L-lactate dehydrogenase; COG: COG2055; Pfam: PF02615; InterPro: IPR003767; Belongs to the LDH2/MDH2 oxidoreductase family.
     
 0.912
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.908
aspC2
Aminotransferase, class I/II; COG: COG1448; Pfam: PF00155; InterPro: IPR000796.
  
  
 
0.907
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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