| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BvgS_2 | BvgS_3 | HMPREF0758_3254 | HMPREF0758_4824 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.983 |
| BvgS_2 | CsrD | HMPREF0758_3254 | HMPREF0758_1814 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Diguanylate cyclase (GGDEF) domain protein; Pfam: PF00990,PF00563; InterPro: IPR001633. | 0.769 |
| BvgS_2 | Gmr_1 | HMPREF0758_3254 | HMPREF0758_1118 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Diguanylate cyclase (GGDEF) domain protein; COG: COG2200; Pfam: PF00990,PF00563; InterPro: IPR001633. | 0.952 |
| BvgS_2 | arcB | HMPREF0758_3254 | HMPREF0758_1880 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.984 |
| BvgS_2 | atoS | HMPREF0758_3254 | HMPREF0758_4660 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | PAS domain S-box protein; COG: COG2202; Pfam: PF08447,PF00015; InterPro: IPR013655. | 0.969 |
| BvgS_2 | barA | HMPREF0758_3254 | HMPREF0758_0477 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00672,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.982 |
| BvgS_2 | evgS | HMPREF0758_3254 | HMPREF0758_2028 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | 0.982 |
| BvgS_2 | hnr | HMPREF0758_3254 | HMPREF0758_3510 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Protein hnr; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.870 |
| BvgS_2 | rcsD | HMPREF0758_3254 | HMPREF0758_2834 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Hpt domain protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. | 0.956 |
| BvgS_2 | rtn | HMPREF0758_3254 | HMPREF0758_2870 | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | Cyclic diguanylate phosphodiesterase (EAL) domain protein; COG: COG2200; Pfam: PF00563; InterPro: IPR001633. | 0.582 |
| BvgS_3 | BvgS_2 | HMPREF0758_4824 | HMPREF0758_3254 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594. | 0.983 |
| BvgS_3 | CsrD | HMPREF0758_4824 | HMPREF0758_1814 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Diguanylate cyclase (GGDEF) domain protein; Pfam: PF00990,PF00563; InterPro: IPR001633. | 0.922 |
| BvgS_3 | Gmr_1 | HMPREF0758_4824 | HMPREF0758_1118 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Diguanylate cyclase (GGDEF) domain protein; COG: COG2200; Pfam: PF00990,PF00563; InterPro: IPR001633. | 0.885 |
| BvgS_3 | arcB | HMPREF0758_4824 | HMPREF0758_1880 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | PAS domain S-box protein; COG: COG0642; Pfam: PF00989,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.984 |
| BvgS_3 | atoS | HMPREF0758_4824 | HMPREF0758_4660 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | PAS domain S-box protein; COG: COG2202; Pfam: PF08447,PF00015; InterPro: IPR013655. | 0.952 |
| BvgS_3 | barA | HMPREF0758_4824 | HMPREF0758_0477 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00672,PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | 0.977 |
| BvgS_3 | evgS | HMPREF0758_4824 | HMPREF0758_2028 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Response regulator receiver domain protein; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR001638. | 0.998 |
| BvgS_3 | hnr | HMPREF0758_4824 | HMPREF0758_3510 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Protein hnr; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. | 0.871 |
| BvgS_3 | rcsD | HMPREF0758_4824 | HMPREF0758_2834 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Hpt domain protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. | 0.962 |
| BvgS_3 | rtn | HMPREF0758_4824 | HMPREF0758_2870 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00512,PF02518,PF00072,PF01627; InterPro: IPR003594. | Cyclic diguanylate phosphodiesterase (EAL) domain protein; COG: COG2200; Pfam: PF00563; InterPro: IPR001633. | 0.705 |