| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94791.1 | minC | HMPREF0758_3662 | HMPREF0758_3459 | Hypothetical protein; 2.4.-.-. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.447 |
| EFE94791.1 | minD | HMPREF0758_3662 | HMPREF0758_3458 | Hypothetical protein; 2.4.-.-. | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | 0.442 |
| EFE94791.1 | mreC | HMPREF0758_3662 | HMPREF0758_1816 | Hypothetical protein; 2.4.-.-. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.820 |
| EFE94791.1 | mreD | HMPREF0758_3662 | HMPREF0758_1817 | Hypothetical protein; 2.4.-.-. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.454 |
| lolA | mreC | HMPREF0758_4449 | HMPREF0758_1816 | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.722 |
| maf | mreB | HMPREF0758_1818 | HMPREF0758_1815 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Rod shape-determining protein MreB; COG: COG1077; Pfam: PF06723; InterPro: IPR004753. | 0.614 |
| maf | mreC | HMPREF0758_1818 | HMPREF0758_1816 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.877 |
| maf | mreD | HMPREF0758_1818 | HMPREF0758_1817 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.940 |
| minC | EFE94791.1 | HMPREF0758_3459 | HMPREF0758_3662 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Hypothetical protein; 2.4.-.-. | 0.447 |
| minC | minD | HMPREF0758_3459 | HMPREF0758_3458 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | 0.999 |
| minC | mreB | HMPREF0758_3459 | HMPREF0758_1815 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Rod shape-determining protein MreB; COG: COG1077; Pfam: PF06723; InterPro: IPR004753. | 0.453 |
| minC | mreC | HMPREF0758_3459 | HMPREF0758_1816 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.862 |
| minC | mreD | HMPREF0758_3459 | HMPREF0758_1817 | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.840 |
| minD | EFE94791.1 | HMPREF0758_3458 | HMPREF0758_3662 | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | Hypothetical protein; 2.4.-.-. | 0.442 |
| minD | minC | HMPREF0758_3458 | HMPREF0758_3459 | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.999 |
| minD | mreB | HMPREF0758_3458 | HMPREF0758_1815 | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | Rod shape-determining protein MreB; COG: COG1077; Pfam: PF06723; InterPro: IPR004753. | 0.521 |
| minD | mreC | HMPREF0758_3458 | HMPREF0758_1816 | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | 0.727 |
| minD | mreD | HMPREF0758_3458 | HMPREF0758_1817 | Septum site-determining protein MinD; COG: COG2894; Pfam: PF01656; InterPro: IPR010223. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.694 |
| mrdA-2 | mrdA-3 | HMPREF0758_3673 | HMPREF0758_4916 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.902 |
| mrdA-2 | mrdB | HMPREF0758_3673 | HMPREF0758_4917 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.939 |