STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aaeAEfflux transporter, RND family, MFP subunit; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (311 aa)    
Predicted Functional Partners:
aaeB
Fusaric acid resistance protein conserved region; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
 
  
 0.948
aaeX
Hypothetical protein; Pfam: PF07869; InterPro: IPR012451.
 
    0.895
macB
ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.839
MdtP
Efflux transporter, outer membrane factor lipoprotein, NodT family; COG: COG1538; Pfam: PF02321; InterPro: IPR010131.
 
 
 0.702
OprM
Efflux transporter, outer membrane factor lipoprotein, NodT family; COG: COG1538; Pfam: PF02321; InterPro: IPR010131.
 
 
 0.679
EFE94334.1
Fusaric acid resistance protein conserved region; COG: COG1289; Pfam: PF04632; InterPro: IPR006726.
 
  
 0.608
tolC
Type I secretion outer membrane protein, TolC family; COG: COG1538; Pfam: PF02321; InterPro: IPR010130.
 
 
 0.568
mdtA
Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; overlaps another CDS with the same product name; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.536
YhcO
Barstar (barnase inhibitor); COG: COG2732; Pfam: PF01337.
 
    0.525
emrB
Multidrug resistance protein B; COG: COG0477; Pfam: PF07690; InterPro: IPR004638; Belongs to the major facilitator superfamily.
  
 
 0.525
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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