STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)    
Predicted Functional Partners:
dctD
Sigma-54 interaction domain protein; COG: COG2204; Pfam: PF00072,PF00158; InterPro: IPR002078.
 
 
 0.958
pspF
Psp operon transcriptional activator; COG: COG1221; Pfam: PF00158,PF02954; InterPro: IPR014317.
 
 
 
 0.950
lepB
Signal peptidase I; COG: COG0681; Pfam: PF00717; InterPro: IPR011056; Belongs to the peptidase S26 family.
  
  
 0.938
levR
Sigma-54 interaction domain protein; Pfam: PF00158,PF00874; InterPro: IPR002078.
 
 
 
 0.923
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.909
yfhK
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; COG: COG0642; Pfam: PF00672,PF00512,PF02518; InterPro: IPR003594.
   
 
 0.903
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.902
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.885
ptsN
PTS IIA-like nitrogen-regulatory protein PtsN; COG: COG1762; Pfam: PF00359; InterPro: IPR002178.
 
  
 0.878
raiA-2
Ribosomal subunit interface protein; COG: COG1544; Pfam: PF02482; InterPro: IPR003489.
  
  
 0.851
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.