STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degQPutative periplasmic serine peptidase DegS; COG: COG0265; Pfam: PF00089,PF00595; InterPro: IPR011782; Belongs to the peptidase S1C family. (455 aa)    
Predicted Functional Partners:
mclA
Anti sigma-E protein RseA domain protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic pro [...]
  
 
 0.729
ompA3
OmpA-like transmembrane domain protein; COG: COG2885; Pfam: PF01389,PF00691; InterPro: IPR000498; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.681
ompA4
Tat pathway signal sequence domain protein; COG: COG2885; Pfam: PF01389,PF00691; InterPro: IPR000498; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.681
degS
Periplasmic serine peptidase DegS; COG: COG0265; Pfam: PF00089,PF00595; InterPro: IPR011783.
 
    
0.607
YhcB
Hypothetical protein; COG: COG3105; Pfam: PF06295; InterPro: IPR009386.
 
   
 0.542
rseP
RIP metalloprotease RseP; COG: COG0750; Pfam: PF02163,PF00595; InterPro: IPR004387.
 
  
 0.529
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.518
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.513
lepB
Signal peptidase I; COG: COG0681; Pfam: PF00717; InterPro: IPR011056; Belongs to the peptidase S26 family.
 
   
 0.511
BvgS_2
PAS domain S-box protein; COG: COG0642; Pfam: PF08448,PF00512,PF02518,PF00072; InterPro: IPR003594.
  
  
 0.508
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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